Research
Our research has been published in leading scientific journals, reflecting our dedication to advancing the understanding of cancer and aging biology.
Highlighted
The Hallmarks of Aging
Cell
·
01 Jun 2013
·
doi:10.1016/j.cell.2013.05.039
Hallmarks of Health
Cell
·
01 Jan 2021
·
doi:10.1016/j.cell.2020.11.034
From geroscience to precision geromedicine Understanding and managing aging
Cell
·
01 Apr 2025
·
doi:10.1016/j.cell.2025.03.011
All
2026
The prevalence and clinical significance of clonal monocytosis
Blood Journal
·
09 Mar 2026
·
doi:10.1182/blood.2025031883
FAβ-gal: an automated fluorescence-based quantification of the senescence-associated beta-galactosidase X-gal assay
openRxiv
·
02 Mar 2026
·
doi:10.64898/2026.02.27.707795
2025
Autophagy: The Last Antioxidant to Unravel
Antioxidants
·
17 Oct 2025
·
doi:10.3390/antiox14101244
ATG4D loss leads to late-onset cardiomyopathy and stress-induced heart failure in mice, and its repression marks maladaptive cardiac remodeling in humans
openRxiv
·
30 Sep 2025
·
doi:10.1101/2025.09.29.678527
Pathological aging is alleviated by neutralization of the autophagy-repressive tissue hormone DBI/ACBP
Autophagy
·
01 Sep 2025
·
doi:10.1080/15548627.2025.2549451
Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis
Nature Genetics
·
28 Aug 2025
·
doi:10.1038/s41588-025-02296-x
Oxidative Stress in the Regulation of Autosis-Related Proteins
Antioxidants
·
04 Aug 2025
·
doi:10.3390/antiox14080958
Acyl-CoA-binding protein as a driver of pathological aging
Proceedings of the National Academy of Sciences
·
07 Jul 2025
·
doi:10.1073/pnas.2501584122
CHIC: A machine learning framework for inferring the presence of high‐risk clonal hematopoiesis using complete blood count data from 431,531 UK Biobank participants
HemaSphere
·
01 Jul 2025
·
doi:10.1002/hem3.70169
Causal relevance of clonal haematopoiesis with cardiac disease and adverse remodelling: a Mendelian randomisation study
Open Heart
·
01 Jul 2025
·
doi:10.1136/openhrt-2025-003602
Exosomes, autophagy, and cancer: A complex triad
International Journal of Cancer
·
02 May 2025
·
doi:10.1002/ijc.35388
Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
Nature
·
16 Apr 2025
·
doi:10.1038/s41586-025-08980-6
From geroscience to precision geromedicine Understanding and managing aging
Cell
·
01 Apr 2025
·
doi:10.1016/j.cell.2025.03.011
Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1
Nature
·
19 Feb 2025
·
doi:10.1038/s41586-025-08590-2
Combined loss of ATG4B, ATG4C and ATG4D impairs systemic autophagy and triggers accelerated aging in mice
openRxiv
·
27 Jan 2025
·
doi:10.1101/2025.01.25.634746
The vocabulary of geromedicine: gerovocabulary
Geromedicine
·
01 Jan 2025
·
doi:10.70401/Geromedicine.2025.0002
Hallmarks of aging: Integrating molecular and social determinants
Geromedicine
·
01 Jan 2025
·
doi:10.70401/Geromedicine.2025.0007
2024
Autophagy Alterations in White and Brown Adipose Tissues of Mice Exercised under Different Training Protocols
Frontiers in Bioscience-Landmark
·
08 Oct 2024
·
doi:10.31083/j.fbl2910348
Noncoding RNA Contribution to Aging and Lifespan
The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
·
23 Feb 2024
·
doi:10.1093/gerona/glae058
Inherited polygenic effects on common hematological traits influence clonal selection on JAK2V617F and the development of myeloproliferative neoplasms
Nature Genetics
·
17 Jan 2024
·
doi:10.1038/s41588-023-01638-x
The hallmarks of aging as a conceptual framework for health and longevity research
Frontiers in Aging
·
15 Jan 2024
·
doi:10.3389/FRAGI.2024.1334261
2023
Prevalence and significance of DDX41 gene variants in the general population
Blood
·
05 Oct 2023
·
doi:10.1182/blood.2023020209
Author Correction: Multiparameter prediction of myeloid neoplasia risk
Nature Genetics
·
19 Sep 2023
·
doi:10.1038/s41588-023-01532-6
Multiparameter prediction of myeloid neoplasia risk
Nature Genetics
·
24 Aug 2023
·
doi:10.1038/s41588-023-01472-1
Genetic Predisposition to Clonal Hematopoiesis
HemaSphere
·
17 Aug 2023
·
doi:10.1097/HS9.0000000000000947
P442: DDX41 GERMLINE VARIANTS: POPULATION PREVALENCE, SIGNIFICANCE AND LEUKEMIC EVOLUTION
HemaSphere
·
08 Aug 2023
·
pmc:PMC10429352
table s4 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433430
table s4 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433430.v1
table s1 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433433.v1
table s1 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433433
Table S5 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433436
Table S5 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433436.v1
Table S3 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433439.v1
Table S3 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433439
Table S2 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433442
Table S2 from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433442.v1
Supplementary Data from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433445.v1
Supplementary Data from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.22433445
Data from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.c.6514368
Data from The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
American Association for Cancer Research (AACR)
·
31 Mar 2023
·
doi:10.1158/0008-5472.c.6514368.v1
Personalized Precision Medicine for Health Care Professionals: Development of a Competency Framework
JMIR Medical Education
·
07 Feb 2023
·
doi:10.2196/43656
USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
Cell Death & Disease
·
26 Jan 2023
·
doi:10.1038/s41419-023-05600-x
2022
Correction: ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution
Blood Cancer Journal
·
06 Dec 2022
·
doi:10.1038/s41408-022-00762-x
The Oncogenic FOXL2 C134W Mutation Is a Key Driver of Granulosa Cell Tumors
Cancer Research
·
21 Nov 2022
·
doi:10.1158/0008-5472.CAN-22-1880
Personalized Precision Medicine for Health Care Professionals: Development of a Competency Framework (Preprint)
JMIR Publications Inc.
·
19 Oct 2022
·
doi:10.2196/preprints.43656
Clonal hematopoiesis is not significantly associated with COVID-19 disease severity
Blood
·
06 Oct 2022
·
doi:10.1182/blood.2022015721
Autophagy‐linked plasma and lysosomal membrane protein
PLAC8
is a key host factor for
SARS‐CoV
‐2 entry into human cells
The EMBO Journal
·
04 Oct 2022
·
doi:10.15252/embj.2022110727
Autophagy alterations in white and brown adipose tissues of mice exercised under different training protocols
openRxiv
·
05 Sep 2022
·
doi:10.1101/2022.09.05.505110
Molecular map of chronic lymphocytic leukemia and its impact on outcome
Nature Genetics
·
04 Aug 2022
·
doi:10.1038/S41588-022-01140-W
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
Nature Medicine
·
01 Aug 2022
·
doi:10.1038/S41591-022-01927-8
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy
Journal of Clinical Investigation
·
15 Jul 2022
·
doi:10.1172/JCI157504
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis
Nature Genetics
·
14 Jul 2022
·
doi:10.1038/s41588-022-01121-z
Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective
Frontiers in Cell and Developmental Biology
·
27 Jun 2022
·
doi:10.3389/FCELL.2022.891332
ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution
Blood Cancer Journal
·
07 Jun 2022
·
doi:10.1038/s41408-022-00686-6
The cancer genome
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology
·
31 May 2022
·
[no id info]
The cancer genome
Cancer: Principles & Practice of Oncology: Primer of the Molecular Biology of Cancer: Second Edition
·
29 May 2022
·
[no id info]
Metabolic gene polymorphisms and lung cancer risk | Influencia de los polimorfismos en genes de metabolización de carcinógenos y riesgo de cáncer de pulmón
Mapfre Medicina
·
26 May 2022
·
[no id info]
Expression of matrix metalloproteinases 1 and 2 genes in a possible association with metastatic abilities of human pancreatic cancer cells
International Journal of Oncology
·
24 May 2022
·
[no id info]
One-step sandwich enzyme immunoassays for human matrix metalloproteinase 13 (collagenase-3) using monoclonal antibodies
Connective Tissue
·
24 May 2022
·
[no id info]
Matrix metalloproteinases as emerging targets for cancer therapy
Clinical and Translational Oncology
·
24 May 2022
·
[no id info]
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy
·
24 May 2022
·
[no id info]
RFcaller: a machine learning approach combined with read-level features to detect somatic mutations
openRxiv
·
12 May 2022
·
doi:10.1101/2022.05.11.491496
NPM1 gene mutations can be confidently identified in blood DNA months before de novo AML onset
Blood Advances
·
08 Apr 2022
·
doi:10.1182/bloodadvances.2021005927
PanCancer analysis of somatic mutations in repetitive regions reveals recurrent mutations in snRNA U2
npj Genomic Medicine
·
14 Mar 2022
·
doi:10.1038/S41525-022-00292-2
Genome-wide analyses of 200,453 individuals yields new insights into the causes and consequences of clonal hematopoiesis
openRxiv
·
06 Jan 2022
·
doi:10.1101/2022.01.06.22268846
Studying Autophagy In Vivo in the Mammary Gland and in Xenograft Samples
Methods in Molecular Biology
·
01 Jan 2022
·
doi:10.1007/978-1-0716-2071-7_16
Characterization of primary and immortalized whale Müller Glial cells
Acta Ophthalmologica
·
01 Jan 2022
·
doi:10.1111/J.1755-3768.2022.216
2021
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy
openRxiv
·
21 Dec 2021
·
doi:10.1101/2021.12.21.473493
Versatility of Protocols for Resistance Training and Assessment Using Static and Dynamic Ladders in Animal Models
Journal of Visualized Experiments
·
17 Dec 2021
·
doi:10.3791/63098
Altered regulation of
BRCA1
exon 11 splicing is associated with breast cancer risk in carriers of
BRCA1
pathogenic variants
Human Mutation
·
31 Aug 2021
·
doi:10.1002/HUMU.24276
Autophagy in major human diseases
The EMBO Journal
·
30 Aug 2021
·
doi:10.15252/EMBJ.2021108863
Autophagy Deficiency by Atg4B Loss Leads to Metabolomic Alterations in Mice
Metabolites
·
27 Jul 2021
·
doi:10.3390/metabo11080481
Enhanced autophagy in Becn1F121A/F121A knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction
Autophagy
·
08 Jun 2021
·
doi:10.1080/15548627.2021.1936358
IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics
Blood
·
27 May 2021
·
doi:10.1182/blood.2020008311
ATG4D role in mAtg8s delipidation and neuroprotection
Autophagy
·
07 May 2021
·
doi:10.1080/15548627.2021.1922979
Old Paradoxes and New Opportunities for Appetite Control in Obesity
Trends in Endocrinology & Metabolism
·
01 May 2021
·
doi:10.1016/j.tem.2021.02.005
ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration
Cell Death & Differentiation
·
01 Apr 2021
·
doi:10.1038/S41418-021-00776-1
mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies
Communications Biology
·
29 Mar 2021
·
doi:10.1038/s42003-021-01938-0
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy
·
02 Jan 2021
·
doi:10.1080/15548627.2020.1797280
Hallmarks of Health
Cell
·
01 Jan 2021
·
doi:10.1016/j.cell.2020.11.034
Hallmarks of Health
Cell
·
01 Jan 2021
·
doi:10.1016/J.CELL.2020.11.034
2020
Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation
The EMBO Journal
·
17 Nov 2020
·
doi:10.15252/EMBJ.2020105074
Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering‐induced Oma1 activation
The EMBO Journal
·
17 Nov 2020
·
doi:10.15252/embj.2020105074
The IGLV3-21R110 Defines a Subset of Chronic Lymphocytic Leukemia with Intermediate Epigenetic Subtype and Poor Outcome
Blood
·
05 Nov 2020
·
doi:10.1182/BLOOD-2020-134786
The CLL-1100 Project: Towards Complete Genomic Characterization and Improved Prognostics for CLL
Blood
·
05 Nov 2020
·
doi:10.1182/BLOOD-2020-140987
Pathogenic Single Nucleotide Polymorphisms on Autophagy-Related Genes
International Journal of Molecular Sciences
·
02 Nov 2020
·
doi:10.3390/ijms21218196
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome
Nature Cancer
·
02 Nov 2020
·
doi:10.1038/S43018-020-00131-2
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome
Nature Cancer
·
02 Nov 2020
·
doi:10.1038/s43018-020-00131-2
Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma
Nature Communications
·
27 Oct 2020
·
doi:10.1038/s41467-020-19175-0
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Nature Communications
·
21 Sep 2020
·
doi:10.1038/s41467-020-18151-y
Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes
Blood
·
17 Sep 2020
·
doi:10.1182/blood.2020005289
Sex differences in oncogenic mutational processes
Nature Communications
·
28 Aug 2020
·
doi:10.1038/s41467-020-17359-2
Sex differences in oncogenic mutational processes
Nature Communications
·
28 Aug 2020
·
doi:10.1038/S41467-020-17359-2
Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage
Science
·
21 Aug 2020
·
doi:10.1126/science.aax0701
Abstract 169: Discovery of clinically distinct CLL subgroups by integrative mapping of large-scale genetic, epigenetic, expression and clinical data
Cancer Research
·
15 Aug 2020
·
doi:10.1158/1538-7445.AM2020-169
Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging
Aging Cell
·
30 Jul 2020
·
doi:10.1111/acel.13203
IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms
Nature Communications
·
07 Jul 2020
·
doi:10.1038/s41467-020-17095-7
Circulating tumor cells for comprehensive and multiregional non-invasive genetic characterization of multiple myeloma
Leukemia
·
01 Jun 2020
·
doi:10.1038/s41375-020-0883-0
Retrograde signals from endosymbiotic organelles: a common control principle in eukaryotic cells
Philosophical Transactions of the Royal Society B: Biological Sciences
·
04 May 2020
·
doi:10.1098/rstb.2019.0396
Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury
Journal of Clinical Investigation
·
04 May 2020
·
doi:10.1172/JCI132366
Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease
neurogenetics
·
28 Apr 2020
·
doi:10.1007/S10048-020-00609-2
Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease
neurogenetics
·
28 Apr 2020
·
doi:10.1007/s10048-020-00609-2
Timing the initiation of multiple myeloma
Nature Communications
·
21 Apr 2020
·
doi:10.1038/s41467-020-15740-9
Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML
Nature Communications
·
16 Mar 2020
·
doi:10.1038/s41467-020-15220-0
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome
openRxiv
·
07 Feb 2020
·
doi:10.1101/2020.02.06.937383
Pan-cancer analysis of whole genomes
Nature
·
05 Feb 2020
·
doi:10.1038/s41586-020-1969-6
Minimal spatial heterogeneity in chronic lymphocytic leukemia at diagnosis
Leukemia
·
04 Feb 2020
·
doi:10.1038/s41375-020-0730-3
Immunosuppression by Mutated Calreticulin Released from Malignant Cells
Molecular Cell
·
01 Feb 2020
·
doi:10.1016/j.molcel.2019.11.004
Genomic and Epigenomic Alterations in Chronic Lymphocytic Leukemia
Annual Review of Pathology: Mechanisms of Disease
·
24 Jan 2020
·
doi:10.1146/annurev-pathmechdis-012419-032810
Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia
JCI Insight
·
16 Jan 2020
·
doi:10.1172/jci.insight.133282
The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance
The FASEB Journal
·
05 Jan 2020
·
doi:10.1096/FJ.201902127R
Partial Loss of USP9X Function Leads to a Male Neurodevelopmental and Behavioral Disorder Converging on Transforming Growth Factor β Signaling
Biological Psychiatry
·
01 Jan 2020
·
doi:10.1016/j.biopsych.2019.05.028
Ubiquitin-specific proteases as targets for anticancer drug therapies
Cancer-Leading Proteases
·
01 Jan 2020
·
doi:10.1016/B978-0-12-818168-3.00004-8
2019
Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
Cell Metabolism
·
01 Dec 2019
·
doi:10.1016/j.cmet.2019.10.011
Cryptic insertions of the immunoglobulin light chain enhancer region near CCND1 in t(11;14)-negative mantle cell lymphoma
Haematologica
·
21 Nov 2019
·
doi:10.3324/haematol.2019.237073
Autophagy is required for performance adaptive response to resistance training and exercise‐induced adult neurogenesis
Scandinavian Journal of Medicine & Science in Sports
·
13 Nov 2019
·
doi:10.1111/sms.13586
Timing the Initiation of Multiple Myeloma
Blood
·
13 Nov 2019
·
doi:10.1182/BLOOD-2019-124357
The U1 Spliceosomal RNA: A Novel Non-Coding Hotspot Driver Mutation Independently Associated with Clinical Outcome in Chronic Lymphocytic Leukemia
Blood
·
13 Nov 2019
·
doi:10.1182/BLOOD-2019-130052
Igcaller: Reconstructing the Rearranged Immunoglobulin Gene in Lymphoid Neoplasms from Whole-Genome Sequencing Data
Blood
·
13 Nov 2019
·
doi:10.1182/BLOOD-2019-130071
Circulating Tumor Cells (CTCs) for Comprehensive and Multiregional Non-Invasive Genetic Characterization of Multiple Myeloma (MM)
Blood
·
13 Nov 2019
·
doi:10.1182/BLOOD-2019-126527
RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing
Haematologica
·
24 Oct 2019
·
doi:10.3324/haematol.2019.230821
Differential mechanisms of tolerance to extreme environmental conditions in tardigrades
Scientific Reports
·
17 Oct 2019
·
doi:10.1038/s41598-019-51471-8
Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells
Oncogene
·
15 Oct 2019
·
doi:10.1038/s41388-019-1053-6
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma
Nature
·
09 Oct 2019
·
doi:10.1038/s41586-019-1650-0
The U1 spliceosomal RNA is recurrently mutated in multiple cancers
Nature
·
09 Oct 2019
·
doi:10.1038/s41586-019-1651-z
Timing the initiation of multiple myeloma
Clinical Lymphoma Myeloma and Leukemia
·
01 Oct 2019
·
doi:10.1016/J.CLML.2019.09.008
Circulating Tumor Cells (CTCs) for Comprehensive and Multiregional Non-Invasive Genetic Characterization of Multiple Myeloma (MM)
Clinical Lymphoma Myeloma and Leukemia
·
01 Oct 2019
·
doi:10.1016/J.CLML.2019.09.580
Global Proteome of LonP1+/− Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes
International Journal of Molecular Sciences
·
12 Sep 2019
·
doi:10.3390/IJMS20184523
Global Proteome of LonP1+/− Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes
International Journal of Molecular Sciences
·
12 Sep 2019
·
doi:10.3390/ijms20184523
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
Cell Stem Cell
·
01 Sep 2019
·
doi:10.1016/j.stem.2019.06.007
Comprehensive autophagy evaluation in cardiac disease models
Cardiovascular Research
·
27 Aug 2019
·
doi:10.1093/cvr/cvz233
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
Cell Research
·
23 Aug 2019
·
doi:10.1038/s41422-019-0213-0
Chromosome 12p Amplification in Triple-Negative/
BRCA1-
Mutated Breast Cancer Associates with Emergence of Docetaxel Resistance and Carboplatin Sensitivity
Cancer Research
·
15 Aug 2019
·
doi:10.1158/0008-5472.can-18-3835
Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics
Nature Communications
·
09 Aug 2019
·
doi:10.1038/s41467-019-11582-2
Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Nature Medicine
·
22 Jul 2019
·
doi:10.1038/S41591-019-0504-5
Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Nature Medicine
·
22 Jul 2019
·
doi:10.1038/s41591-019-0504-5
A practical guide for mutational signature analysis in hematological malignancies
Nature Communications
·
05 Jul 2019
·
doi:10.1038/s41467-019-11037-8
Decelerating ageing and biological clocks by autophagy
Nature Reviews Molecular Cell Biology
·
04 Jun 2019
·
doi:10.1038/s41580-019-0149-8
Moving Frailty Toward Clinical Practice: NIA Intramural Frailty Science Symposium Summary
Journal of the American Geriatrics Society
·
02 May 2019
·
doi:10.1111/jgs.15928
Association of the POT1 Germline Missense Variant p.I78T With Familial Melanoma
JAMA Dermatology
·
01 May 2019
·
doi:10.1001/jamadermatol.2018.3662
Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells
EMBO Molecular Medicine
·
12 Mar 2019
·
doi:10.15252/emmm.201809736
Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo
Journal of Molecular and Cellular Cardiology
·
01 Mar 2019
·
doi:10.1016/J.YJMCC.2018.12.017
Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo
Journal of Molecular and Cellular Cardiology
·
01 Mar 2019
·
doi:10.1016/j.yjmcc.2018.12.017
CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1− mantle cell lymphoma
Blood
·
28 Feb 2019
·
doi:10.1182/blood-2018-07-862151
Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
Nature Medicine
·
18 Feb 2019
·
doi:10.1038/s41591-018-0338-6
Timing the Initiation of Multiple Myeloma
SSRN Electronic Journal
·
01 Jan 2019
·
doi:10.2139/ssrn.3409453
2018
Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing
Nature Cell Biology
·
17 Dec 2018
·
doi:10.1038/s41556-018-0259-0
Giant tortoise genomes provide insights into longevity and age-related disease
Nature Ecology & Evolution
·
03 Dec 2018
·
doi:10.1038/s41559-018-0733-x
An Epigenetic Mitotic Score Tracks the Proliferative History and Capacity of CLL Samples at Diagnosis and Is Associated with Clinical Outcome
Blood
·
29 Nov 2018
·
doi:10.1182/BLOOD-2018-99-113434
Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms
Blood
·
29 Nov 2018
·
doi:10.1182/BLOOD-2018-99-116015
Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia
Blood
·
29 Nov 2018
·
doi:10.1182/blood-2017-09-804401
Genome Sequencing and Analysis Methods in Chronic Lymphocytic Leukemia
Methods in Molecular Biology
·
23 Oct 2018
·
doi:10.1007/978-1-4939-8876-1_22
The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function
PLOS Biology
·
22 Oct 2018
·
doi:10.1371/journal.pbio.2006247
Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?
Autophagy
·
18 Oct 2018
·
doi:10.1080/15548627.2018.1533059
Specific combinations of biallelic
POLR3A
variants cause Wiedemann-Rautenstrauch syndrome
Journal of Medical Genetics
·
15 Oct 2018
·
doi:10.1136/jmedgenet-2018-105528
Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness
JCI Insight
·
04 Oct 2018
·
doi:10.1172/jci.insight.120920
Carbotoxicity—Noxious Effects of Carbohydrates
Cell
·
01 Oct 2018
·
doi:10.1016/j.cell.2018.07.044
Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia
Haematologica
·
27 Sep 2018
·
doi:10.3324/haematol.2018.196931
Mouse Models to Disentangle the Hallmarks of Human Aging
Circulation Research
·
14 Sep 2018
·
doi:10.1161/circresaha.118.312204
Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism
Cell Reports
·
01 Aug 2018
·
doi:10.1016/J.CELREP.2018.07.089
Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism
Cell Reports
·
01 Aug 2018
·
doi:10.1016/j.celrep.2018.07.089
Vascular Smooth Muscle–Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome
Circulation
·
17 Jul 2018
·
doi:10.1161/CIRCULATIONAHA.117.030856
Germline variation in the oxidative DNA repair genesNUDT1andOGG1is not associated with hereditary colorectal cancer or polyposis
Human Mutation
·
04 Jul 2018
·
doi:10.1002/humu.23564
Collagenase-2 deficiency or inhibition impairs experimental autoimmune encephalomyelitis in mice.
Journal of Biological Chemistry
·
01 Jul 2018
·
doi:10.1074/jbc.AAC118.004703
ADAMTS-12 metalloprotease is necessary for normal inflammatory response.
Journal of Biological Chemistry
·
01 Jul 2018
·
doi:10.1074/jbc.AAC118.004590
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Journal of Biological Chemistry
·
01 Jul 2018
·
doi:10.1074/jbc.AAC118.004704
Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species
Cell Systems
·
01 Jun 2018
·
doi:10.1016/j.cels.2018.05.016
Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes
Cell Systems
·
01 Jun 2018
·
doi:10.1016/j.cels.2018.05.009
Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice
Nature
·
30 May 2018
·
doi:10.1038/S41586-018-0162-7
Chronic lymphocytic leukemia and mantle cell lymphoma: crossroads of genetic and microenvironment interactions
Blood
·
24 May 2018
·
doi:10.1182/blood-2017-10-764373
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia
Nature Medicine
·
21 May 2018
·
doi:10.1038/s41591-018-0028-4
Matriptase-2 deficiency protects from obesity by modulating iron homeostasis
Nature Communications
·
10 Apr 2018
·
doi:10.1038/s41467-018-03853-1
Increased autophagy blocks HER2-mediated breast tumorigenesis
Proceedings of the National Academy of Sciences
·
02 Apr 2018
·
doi:10.1073/pnas.1717800115
Ablation of the stress protease OMA1 protects against heart failure in mice
Science Translational Medicine
·
28 Mar 2018
·
doi:10.1126/scitranslmed.aan4935
Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
Nature Communications
·
06 Mar 2018
·
doi:10.1038/s41467-018-03433-3
Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver
Aging Cell
·
27 Feb 2018
·
doi:10.1111/acel.12742
Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis
Molecular Cancer
·
15 Feb 2018
·
doi:10.1186/s12943-018-0762-8
Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice
Journal of Biological Chemistry
·
01 Feb 2018
·
doi:10.1074/jbc.M117.788430
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Cell Death & Differentiation
·
23 Jan 2018
·
doi:10.1038/s41418-017-0012-4
Mitohormesis, an Antiaging Paradigm
International Review of Cell and Molecular Biology
·
01 Jan 2018
·
doi:10.1016/BS.IRCMB.2018.05.002
Mitohormesis, an Antiaging Paradigm
International Review of Cell and Molecular Biology
·
01 Jan 2018
·
doi:10.1016/bs.ircmb.2018.05.002
Determination of Aconitase Activity: A Substrate of the Mitochondrial Lon Protease
Methods in Molecular Biology
·
01 Jan 2018
·
doi:10.1007/978-1-4939-7595-2_5
Autophagy and Proteases: Basic Study of the Autophagic Flux by Western Blot
Methods in Molecular Biology
·
01 Jan 2018
·
doi:10.1007/978-1-4939-7595-2_8
Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer
Gastroenterology
·
01 Jan 2018
·
doi:10.1053/j.gastro.2017.09.005
Dissecting Degradomes: Analysis of Protease-Coding Genes
Methods in Molecular Biology
·
01 Jan 2018
·
doi:10.1007/978-1-4939-7595-2_1
Tumor xenograft modeling identifies TCF4/ITF2 loss associated with breast cancer chemoresistance
Disease Models & Mechanisms
·
01 Jan 2018
·
doi:10.1242/dmm.032292
The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging
Stem Cell Genetics for Biomedical Research
·
01 Jan 2018
·
doi:10.1007/978-3-319-90695-9_13
Progeria Mouse Models
Conn's Handbook of Models for Human Aging
·
01 Jan 2018
·
doi:10.1016/B978-0-12-811353-0.00051-8
Protease Silencing to Explore the Molecular Mechanisms of Cancer and Aging
Methods in Molecular Biology
·
01 Jan 2018
·
doi:10.1007/978-1-4939-7595-2_23
2017
Functional relevance of miRNAs in premature ageing
Mechanisms of Ageing and Development
·
01 Dec 2017
·
doi:10.1016/j.mad.2017.05.003
The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress
Nature Communications
·
28 Nov 2017
·
doi:10.1038/s41467-017-01903-8
The mutational landscape of small lymphocytic lymphoma compared to non-early stage chronic lymphocytic leukemia
Leukemia & Lymphoma
·
08 Nov 2017
·
doi:10.1080/10428194.2017.1397660
The role of matrix metalloproteinases in aging: Tissue remodeling and beyond
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
·
01 Nov 2017
·
doi:10.1016/j.bbamcr.2017.05.007
Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP™ DNA microarray
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
·
01 Nov 2017
·
doi:10.1016/j.bbamcr.2017.08.004
Clonal evolution in leukemia
Nature Medicine
·
01 Oct 2017
·
doi:10.1038/nm.4410
A t(1;9) translocation involving
CSF3R
as a novel mechanism in unclassifiable chronic myeloproliferative neoplasm
Haematologica
·
21 Sep 2017
·
doi:10.3324/haematol.2017.176693
Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia
Leukemia
·
19 Sep 2017
·
doi:10.1038/leu.2017.291
The Novel Evolution of the Sperm Whale Genome
Genome Biology and Evolution
·
13 Sep 2017
·
doi:10.1093/gbe/evx187
A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation
Nature Cell Biology
·
31 Aug 2017
·
doi:10.1038/NCB3602
A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation
Nature Cell Biology
·
31 Aug 2017
·
doi:10.1038/ncb3602
Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
Cell Death & Disease
·
03 Aug 2017
·
doi:10.1038/CDDIS.2017.373
Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
Cell Death & Disease
·
03 Aug 2017
·
doi:10.1038/cddis.2017.373
Immune and inflammatory responses to DNA damage in cancer and aging
Mechanisms of Ageing and Development
·
01 Jul 2017
·
doi:10.1016/j.mad.2016.10.004
Molecular definitions of autophagy and related processes
The EMBO Journal
·
08 Jun 2017
·
doi:10.15252/embj.201796697
Mitochondria and Epigenetics – Crosstalk in Homeostasis and Stress
Trends in Cell Biology
·
01 Jun 2017
·
doi:10.1016/j.tcb.2017.02.004
Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
Journal of Cell Biology
·
31 May 2017
·
doi:10.1083/jcb.201702058
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes
Nature Genetics
·
20 Mar 2017
·
doi:10.1038/ng.3817
Analysis of mtDNA/nDNA Ratio in Mice
Current Protocols in Mouse Biology
·
01 Mar 2017
·
doi:10.1002/cpmo.21
USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven Cancer
Journal of Biological Chemistry
·
01 Mar 2017
·
doi:10.1074/jbc.M116.762757
Deubiquitination in cancer stem cells
Aging
·
12 Feb 2017
·
doi:10.18632/aging.101182
Tagged ATG8-Coding Constructs for the In Vitro and In Vivo Assessment of ATG4 Activity
Methods in Enzymology
·
01 Jan 2017
·
doi:10.1016/bs.mie.2016.11.001
Physiological and Pathological Functions of Mitochondrial Proteases
Proteases in Physiology and Pathology
·
01 Jan 2017
·
doi:10.1007/978-981-10-2513-6_1
Functional Relevance of Deubiquitinases in Life and Disease
Proteases in Physiology and Pathology
·
01 Jan 2017
·
doi:10.1007/978-981-10-2513-6_16
2016
Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
Oncogene
·
19 Dec 2016
·
doi:10.1038/onc.2016.427
Clinical Impact of the Quantitative Subclonal Architecture in Chronic Lymphocytic Leukemia
Blood
·
02 Dec 2016
·
doi:10.1182/BLOOD.V128.22.2024.2024
Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx
Genome Biology
·
01 Dec 2016
·
doi:10.1186/s13059-016-1090-1
Cardiac electrical defects in progeroid mice and Hutchinson–Gilford progeria syndrome patients with nuclear lamina alterations
Proceedings of the National Academy of Sciences
·
31 Oct 2016
·
doi:10.1073/pnas.1603754113
The deubiquitinaseUSP54is overexpressed in colorectal cancer stem cells and promotes intestinal tumorigenesis
Oncotarget
·
19 Oct 2016
·
doi:10.18632/oncotarget.12769
Transplacental transfer of essential thrombocythemia in monozygotic twins
Blood
·
06 Oct 2016
·
doi:10.1182/blood-2016-06-724252
Does Autophagy Mediate Cardiac Myocyte Death During Stress?
Circulation Research
·
30 Sep 2016
·
doi:10.1161/CIRCRESAHA.116.309765
Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
Journal of Clinical Investigation
·
12 Sep 2016
·
doi:10.1172/JCI84164
Congenital dilated cardiomyopathy caused by biallelic mutations in Filamin C
European Journal of Human Genetics
·
07 Sep 2016
·
doi:10.1038/ejhg.2016.110
iPSCs: On the Road to Reprogramming Aging
Trends in Molecular Medicine
·
01 Aug 2016
·
doi:10.1016/j.molmed.2016.05.010
Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism
Cell Reports
·
01 Aug 2016
·
doi:10.1016/j.celrep.2016.07.053
Metabolic Control of Longevity
Cell
·
01 Aug 2016
·
doi:10.1016/j.cell.2016.07.031
Age-driven developmental drift in the pathogenesis of idiopathic pulmonary fibrosis
European Respiratory Journal
·
07 Jul 2016
·
doi:10.1183/13993003.00398-2016
Proteostasis alterations in myeloproliferative neoplasms: Oncogenic relevance and therapeutic opportunities
Experimental Hematology
·
01 Jul 2016
·
doi:10.1016/j.exphem.2016.04.004
MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling
The Journal of Immunology
·
01 Jul 2016
·
doi:10.4049/jimmunol.1600094
Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells
Disease Models & Mechanisms
·
01 Jul 2016
·
doi:10.1242/dmm.024711
Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation
Journal of Medical Genetics
·
22 Jun 2016
·
doi:10.1136/JMEDGENET-2015-103695
Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation
Journal of Medical Genetics
·
22 Jun 2016
·
doi:10.1136/jmedgenet-2015-103695
Non-coding recurrent mutations in chronic lymphocytic leukaemia
Nature
·
01 Jun 2016
·
doi:10.1038/nature18910
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
Cell
·
01 May 2016
·
doi:10.1016/j.cell.2016.04.012
Fanconi Anemia Proteins Function in Mitophagy and Immunity
Cell
·
01 May 2016
·
doi:10.1016/J.CELL.2016.04.006
Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia
Blood
·
28 Apr 2016
·
doi:10.1182/blood-2015-07-659144
POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance
Genetics in Medicine
·
01 Apr 2016
·
doi:10.1038/gim.2015.75
Impact of the functional CD5 polymorphism A471V on the response of chronic lymphocytic leukaemia to conventional chemotherapy regimens
British Journal of Haematology
·
15 Mar 2016
·
doi:10.1111/bjh.14037
Mitonuclear communication in homeostasis and stress
Nature Reviews Molecular Cell Biology
·
09 Mar 2016
·
doi:10.1038/nrm.2016.23
A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features
Nature Communications
·
01 Mar 2016
·
doi:10.1038/ncomms10815
The novel tumor suppressor AIRAPL regulates IGF1R proteostasis
Cell Cycle
·
22 Feb 2016
·
doi:10.1080/15384101.2016.1151725
Pharmacogenetics and pharmacogenomics as tools in cancer therapy
Drug Metabolism and Personalized Therapy
·
10 Feb 2016
·
doi:10.1515/dmpt-2015-0042
Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis
Scientific Reports
·
08 Feb 2016
·
doi:10.1038/srep20697
Erratum
Autophagy
·
01 Feb 2016
·
doi:10.1080/15548627.2016.1147886
Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria
Journal of Cell Biology
·
18 Jan 2016
·
doi:10.1083/jcb.201507022
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy
·
02 Jan 2016
·
doi:10.1080/15548627.2015.1100356
NF-κB signaling as a driver of ageing
International Review of Cell and Molecular Biology
·
01 Jan 2016
·
doi:10.1016/bs.ircmb.2016.04.003
2015
Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling
Nature Medicine
·
21 Dec 2015
·
doi:10.1038/nm.4013
Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes
Oncotarget
·
20 Dec 2015
·
doi:10.18632/oncotarget.6697
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
Nature Communications
·
09 Dec 2015
·
doi:10.1038/ncomms10001
Clinical Impact of Clonal and Subclonal TP53, SF3B1, BIRC3, and ATM Mutations in Chronic Lymphocytic Leukemia
Blood
·
03 Dec 2015
·
doi:10.1182/BLOOD.V126.23.4138.4138
Chronic lymphocytic leukemia: looking into the dark side of the genome
Cell Death & Differentiation
·
27 Nov 2015
·
doi:10.1038/cdd.2015.155
Molecular mechanisms of normal and pathological aging
Orphanet Journal of Rare Diseases
·
11 Nov 2015
·
doi:10.1186/1750-1172-10-S2-O1
Reprogramming aging through DOT1L inhibition
Cell Cycle
·
02 Nov 2015
·
doi:10.1080/15384101.2015.1093443
Germline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair
Gastroenterology
·
01 Sep 2015
·
doi:10.1053/j.gastro.2015.05.056
NF-κB activation impairs somatic cell reprogramming in ageing
Nature Cell Biology
·
27 Jul 2015
·
doi:10.1038/ncb3207
Non-coding recurrent mutations in chronic lymphocytic leukaemia
Nature
·
22 Jul 2015
·
doi:10.1038/nature14666
Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia
Blood
·
09 Jul 2015
·
doi:10.1182/blood-2014-10-604959
The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia
Oncotarget
·
08 Jun 2015
·
doi:10.18632/oncotarget.4212
Mutations in the Toll-like receptor/MYD88 pathway in young (≤50 years) CLL patients
Clinical Lymphoma Myeloma and Leukemia
·
01 Jun 2015
·
doi:10.1016/J.CLML.2015.04.063
Loss of
MT
1‐
MMP
causes cell senescence and nuclear defects which can be reversed by retinoic acid
The EMBO Journal
·
19 May 2015
·
doi:10.15252/embj.201490594
New roles for mitochondrial proteases in health, ageing and disease
Nature Reviews Molecular Cell Biology
·
13 May 2015
·
doi:10.1038/nrm3984
ADAMTS proteases and cancer
Matrix Biology
·
01 May 2015
·
doi:10.1016/j.matbio.2015.01.013
Common and rare variants of microRNA genes in autism spectrum disorders
The World Journal of Biological Psychiatry
·
23 Apr 2015
·
doi:10.3109/15622975.2015.1029518
Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis
Autophagy
·
03 Apr 2015
·
doi:10.1080/15548627.2015.1034409
Comprehensive establishment and characterization of orthoxenograft mouse models of malignant peripheral nerve sheath tumors for personalized medicine
EMBO Molecular Medicine
·
25 Mar 2015
·
doi:10.15252/emmm.201404430
Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research
Cell Reports
·
01 Mar 2015
·
doi:10.1016/j.celrep.2015.02.034
Erratum: Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis
Leukemia
·
01 Mar 2015
·
doi:10.1038/leu.2014.309
Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer
Oncotarget
·
28 Feb 2015
·
doi:10.18632/oncotarget.3464
Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer
Oncotarget
·
28 Feb 2015
·
doi:10.18632/ONCOTARGET.3464
Molecular pathogenesis of CLL and its evolution
International Journal of Hematology
·
29 Jan 2015
·
doi:10.1007/s12185-015-1733-0
Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine uptake and cytotoxicity in chronic lymphocytic leukemia (CLL) cells
The Pharmacogenomics Journal
·
13 Jan 2015
·
doi:10.1038/tpj.2014.77
The functional and pathologic relevance of autophagy proteases
Journal of Clinical Investigation
·
02 Jan 2015
·
doi:10.1172/JCI73940
Regulatory Roles of miRNAs in Aging
Advances in Experimental Medicine and Biology
·
01 Jan 2015
·
doi:10.1007/978-3-319-22380-3_11
Insights into the Evolution of Longevity from the Bowhead Whale Genome
Cell Reports
·
01 Jan 2015
·
doi:10.1016/j.celrep.2014.12.008
2014
Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma
JNCI: Journal of the National Cancer Institute
·
13 Dec 2014
·
doi:10.1093/jnci/dju408
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Nature
·
10 Dec 2014
·
doi:10.1038/NATURE14136
Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer
Molecular & Cellular Oncology
·
08 Dec 2014
·
doi:10.4161/23723548.2014.968505
A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction
British Journal of Haematology
·
17 Nov 2014
·
doi:10.1111/bjh.13225
Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy
Nature Communications
·
29 Oct 2014
·
doi:10.1038/ncomms6326
Comprehensive characterization of complex structural variations in cancer by directly comparing genome sequence reads
Nature Biotechnology
·
26 Oct 2014
·
doi:10.1038/nbt.3027
Loss of GLUT4 Induces Metabolic Reprogramming and Impairs Viability of Breast Cancer Cells
Journal of Cellular Physiology
·
29 Sep 2014
·
doi:10.1002/jcp.24698
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Cell Death & Differentiation
·
19 Sep 2014
·
doi:10.1038/cdd.2014.137
A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact
Leukemia
·
25 Aug 2014
·
doi:10.1038/leu.2014.252
Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
Frontiers in Immunology
·
20 Aug 2014
·
doi:10.3389/fimmu.2014.00403
The common marmoset genome provides insight into primate biology and evolution
Nature Genetics
·
20 Jul 2014
·
doi:10.1038/ng.3042
Matriptase-2 is essential for hepcidin repression during fetal life and postnatal development in mice to maintain iron homeostasis
Blood
·
17 Jul 2014
·
doi:10.1182/blood-2014-01-551150
ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity
Cell Reports
·
01 Jul 2014
·
doi:10.1016/J.CELREP.2014.06.018
ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity
Cell Reports
·
01 Jul 2014
·
doi:10.1016/j.celrep.2014.06.018
MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin
Nature Cell Biology
·
22 Jun 2014
·
doi:10.1038/ncb2993
Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome
Blood
·
12 Jun 2014
·
doi:10.1182/blood-2013-12-543306
OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury
American Journal of Physiology-Renal Physiology
·
01 Jun 2014
·
doi:10.1152/ajprenal.00036.2014
Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome
BMC Medical Genetics
·
02 May 2014
·
doi:10.1186/1471-2350-15-51
The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells
Leukemia
·
30 Apr 2014
·
doi:10.1038/leu.2014.143
Nuclear Envelope Lamin-A Couples Actin Dynamics with Immunological Synapse Architecture and T Cell Activation
Science Signaling
·
22 Apr 2014
·
doi:10.1126/scisignal.2004872
The prognostic impact of minimal residual disease in patients with chronic lymphocytic leukemia requiring first-line therapy
Haematologica
·
03 Apr 2014
·
doi:10.3324/haematol.2013.099796
Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype
Gut
·
01 Apr 2014
·
doi:10.1136/gutjnl-2014-307084
POT1 loss-of-function variants predispose to familial melanoma
Nature Genetics
·
30 Mar 2014
·
doi:10.1038/ng.2947
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
Genes & Development
·
17 Mar 2014
·
doi:10.1101/gad.237404.114
Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
Molecular Cell
·
01 Mar 2014
·
doi:10.1016/J.MOLCEL.2014.01.016
Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
Molecular Cell
·
01 Mar 2014
·
doi:10.1016/j.molcel.2014.01.016
Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia
Journal of Molecular Medicine
·
19 Feb 2014
·
doi:10.1007/S00109-014-1132-7
Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells
Oncotarget
·
12 Jan 2014
·
doi:10.18632/oncotarget.1690
Progeria: A Paradigm for Translational Medicine
Cell
·
01 Jan 2014
·
doi:10.1016/j.cell.2013.12.028
Functional Relevance of Autophagins in Life and Disease
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging
·
01 Jan 2014
·
doi:10.1016/B978-0-12-405529-2.00007-X
2013
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia
Genome Research
·
21 Nov 2013
·
doi:10.1101/gr.152132.112
Abstract C114: Clinical response to a lapatinib-based therapy of a Li-Fraumeni Syndrome patient with a novel HER2-V659E mutation.
Molecular Cancer Therapeutics
·
01 Nov 2013
·
doi:10.1158/1535-7163.TARG-13-C114
Clinical Response to a Lapatinib-Based Therapy for a Li-Fraumeni Syndrome Patient with a Novel
HER2
V659E Mutation
Cancer Discovery
·
01 Nov 2013
·
doi:10.1158/2159-8290.CD-13-0132
The Emergence of GeroMIRs: A Group of MicroRNAs Implicated in Aging
MicroRNAs in Medicine
·
01 Nov 2013
·
doi:10.1002/9781118300312.ch5
Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas
Oncotarget
·
01 Nov 2013
·
pmc:PMC3875759
Landscape of somatic mutations and clonal evolution in mantle cell lymphoma
Proceedings of the National Academy of Sciences
·
21 Oct 2013
·
doi:10.1073/pnas.1314608110
Cell–cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas
Nature Communications
·
08 Oct 2013
·
doi:10.1038/ncomms3531
Next-Generation Sequencing in Chronic Lymphocytic Leukemia
Seminars in Hematology
·
01 Oct 2013
·
doi:10.1053/j.seminhematol.2013.09.005
Identification of mitochondrial dysfunction in Hutchinson–Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture
Journal of Proteomics
·
01 Oct 2013
·
doi:10.1016/j.jprot.2013.08.008
Erratum: Corrigendum: Signatures of mutational processes in human cancer
Nature
·
01 Oct 2013
·
doi:10.1038/nature12666
Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas
Oncotarget
·
15 Sep 2013
·
doi:10.18632/oncotarget.1303
Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas
Oncotarget
·
15 Sep 2013
·
doi:10.18632/ONCOTARGET.1303
Exome sequencing in multiplex autism families suggests a major role for heterozygous truncating mutations
Molecular Psychiatry
·
03 Sep 2013
·
doi:10.1038/mp.2013.106
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
Autophagy
·
14 Aug 2013
·
doi:10.4161/AUTO.24797
Signatures of mutational processes in human cancer
Nature
·
14 Aug 2013
·
doi:10.1038/nature12477
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
Autophagy
·
14 Aug 2013
·
doi:10.4161/auto.24797
Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion
Nature Communications
·
06 Aug 2013
·
doi:10.1038/ncomms3268
The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21
Oncogene
·
15 Jul 2013
·
doi:10.1038/onc.2013.267
Genetic and epigenetic basis of chronic lymphocytic leukemia
Current Opinion in Hematology
·
01 Jul 2013
·
doi:10.1097/MOH.0b013e32836235dc
A Novel Family of Soluble Minimal Scaffolds Provides Structural Insight into the Catalytic Domains of Integral Membrane Metallopeptidases
Journal of Biological Chemistry
·
01 Jul 2013
·
doi:10.1074/jbc.M113.476580
Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain
Science
·
28 Jun 2013
·
doi:10.1126/science.1230381
Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome That Is Ameliorated on Pyrophosphate Treatment
Circulation
·
18 Jun 2013
·
doi:10.1161/CIRCULATIONAHA.112.000571
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia
Nature Genetics
·
16 Jun 2013
·
doi:10.1038/ng.2652
Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathway
American Journal of Physiology-Lung Cellular and Molecular Physiology
·
15 Jun 2013
·
doi:10.1152/AJPLUNG.00422.2012
The Hallmarks of Aging
Cell
·
01 Jun 2013
·
doi:10.1016/j.cell.2013.05.039
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF
EMBO Molecular Medicine
·
30 May 2013
·
doi:10.1002/emmm.201202100
Matrix metalloprotease 1a deficiency suppresses tumor growth and angiogenesis
Oncogene
·
27 May 2013
·
doi:10.1038/onc.2013.157
Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias (Northern Spain)
BMC Cancer
·
17 May 2013
·
doi:10.1186/1471-2407-13-243
The genomic landscape of chronic lymphocytic leukemia: clinical implications
BMC Medicine
·
09 May 2013
·
doi:10.1186/1741-7015-11-124
Matrix Metalloproteinase Mmp-1a Is Dispensable for Normal Growth and Fertility in Mice and Promotes Lung Cancer Progression by Modulating Inflammatory Responses
Journal of Biological Chemistry
·
01 May 2013
·
doi:10.1074/jbc.M112.439893
Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis
Leukemia
·
24 Apr 2013
·
doi:10.1038/leu.2013.127
Luminescence-based in vivo monitoring of NF-κB activity through a gene delivery approach
Cell Communication and Signaling
·
21 Mar 2013
·
doi:10.1186/1478-811X-11-19
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
Nature Genetics
·
17 Mar 2013
·
doi:10.1038/ng.2584
The evolutionary biography of chronic lymphocytic leukemia
Nature Genetics
·
24 Feb 2013
·
doi:10.1038/ng.2556
Functional analysis of sucrase–isomaltase mutations from chronic lymphocytic leukemia patients
Human Molecular Genetics
·
14 Feb 2013
·
doi:10.1093/hmg/ddt078
Polyserases
Handbook of Proteolytic Enzymes
·
01 Jan 2013
·
doi:10.1016/B978-0-12-382219-2.00653-0
Matrix Metallopeptidase-19
Handbook of Proteolytic Enzymes
·
01 Jan 2013
·
doi:10.1016/B978-0-12-382219-2.00170-8
Matriptase-2
Handbook of Proteolytic Enzymes
·
01 Jan 2013
·
doi:10.1016/B978-0-12-382219-2.00650-5
Immune-Dependent and Independent Antitumor Activity of GM-CSF Aberrantly Expressed by Mouse and Human Colorectal Tumors
Cancer Research
·
01 Jan 2013
·
doi:10.1158/0008-5472.CAN-12-0806
Conquering Cancer in Our Lifetime: New Diagnostic and Therapeutic Trends
Clinical Chemistry
·
01 Jan 2013
·
doi:10.1373/clinchem.2012.186940
Cathepsin O
Handbook of Proteolytic Enzymes
·
01 Jan 2013
·
doi:10.1016/B978-0-12-382219-2.00411-7
Aminopeptidase O
Handbook of Proteolytic Enzymes
·
01 Jan 2013
·
doi:10.1016/B978-0-12-382219-2.00088-0
ADAMTS12
Handbook of Proteolytic Enzymes
·
01 Jan 2013
·
doi:10.1016/B978-0-12-382219-2.00267-2
Recurrent Gene Mutations in CLL
Advances in Experimental Medicine and Biology
·
01 Jan 2013
·
doi:10.1007/978-1-4614-8051-8_4
New roles for OMA1 metalloprotease
Adipocyte
·
01 Jan 2013
·
doi:10.4161/adip.21999
2012
Estimation of Copy Number Alterations from Exome Sequencing Data
PLoS ONE
·
19 Dec 2012
·
doi:10.1371/journal.pone.0051422
NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome
Leukemia
·
06 Dec 2012
·
doi:10.1038/leu.2012.357
Arresten, a Collagen-Derived Angiogenesis Inhibitor, Suppresses Invasion of Squamous Cell Carcinoma
PLoS ONE
·
05 Dec 2012
·
doi:10.1371/journal.pone.0051044
Reprogramming aging and progeria
Current Opinion in Cell Biology
·
01 Dec 2012
·
doi:10.1016/j.ceb.2012.08.009
Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia
Leukemia
·
28 Nov 2012
·
doi:10.1038/leu.2012.344
NF-κB in premature aging
Aging
·
27 Nov 2012
·
doi:10.18632/aging.100502
NF-κB in premature aging
Aging
·
27 Nov 2012
·
doi:10.18632/AGING.100502
ADAMTS-12 Metalloprotease Is Necessary for Normal Inflammatory Response
Journal of Biological Chemistry
·
01 Nov 2012
·
doi:10.1074/jbc.M112.408625
Detection of Nuclear Envelope Alterations in Senescence
Methods in Molecular Biology
·
01 Nov 2012
·
doi:10.1007/978-1-62703-239-1_16
Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection
PLoS Genetics
·
18 Oct 2012
·
doi:10.1371/journal.pgen.1003007
Matrix Metalloproteinase-19 Is a Key Regulator of Lung Fibrosis in Mice and Humans
American Journal of Respiratory and Critical Care Medicine
·
15 Oct 2012
·
doi:10.1164/rccm.201202-0302OC
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
Nature Genetics
·
14 Oct 2012
·
doi:10.1038/ng.2443
Control of Allergen-Induced Inflammation and Hyperresponsiveness by the Metalloproteinase ADAMTS-12
The Journal of Immunology
·
01 Oct 2012
·
doi:10.4049/jimmunol.1103739
An Immunosurveillance Mechanism Controls Cancer Cell Ploidy
Science
·
28 Sep 2012
·
doi:10.1126/science.1224922
Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
Genes & Development
·
26 Sep 2012
·
doi:10.1101/GAD.197954.112
Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
Genes & Development
·
26 Sep 2012
·
doi:10.1101/gad.197954.112
Matrix Metalloprotease 8-Dependent Extracellular Matrix Cleavage at the Blood-CSF Barrier Contributes to Lethality during Systemic Inflammatory Diseases
Journal of Neuroscience
·
18 Jul 2012
·
doi:10.1523/JNEUROSCI.0967-12.2012
Chronic Lymphocytic Leukemia withSF3B1Mutation
New England Journal of Medicine
·
28 Jun 2012
·
doi:10.1056/NEJMc1204033
Matrix Proteases and the Degradome
Matrix Proteases in Health and Disease
·
06 Jun 2012
·
doi:10.1002/9783527649327.ch1
Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma
Cell Host & Microbe
·
01 Apr 2012
·
doi:10.1016/j.chom.2012.03.002
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy
·
01 Apr 2012
·
doi:10.4161/auto.19496
Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice
The EMBO Journal
·
20 Mar 2012
·
doi:10.1038/emboj.2012.70
Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells
Cell Cycle
·
01 Mar 2012
·
doi:10.4161/cc.11.5.19450
Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle
Cell Host & Microbe
·
01 Jan 2012
·
doi:10.1016/j.chom.2011.12.002
New and Paradoxical Roles of Matrix Metalloproteinases in the Tumor Microenvironment
Frontiers in Pharmacology
·
01 Jan 2012
·
doi:10.3389/fphar.2012.00140
2011
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
Nature Genetics
·
11 Dec 2011
·
doi:10.1038/ng.1032
Cell autonomous and systemic factors in progeria development
Biochemical Society Transactions
·
21 Nov 2011
·
doi:10.1042/BST20110677
Cell autonomous and systemic factors in progeria development
Biochemical Society Transactions
·
21 Nov 2011
·
doi:10.1042/bst20110677
Micromanaging aging with miRNAs
Nucleus
·
01 Nov 2011
·
doi:10.4161/nucl.2.6.17986
Proteomic Profiling of Adipose Tissue from Zmpste24−/− Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing
Molecular & Cellular Proteomics
·
01 Nov 2011
·
doi:10.1074/mcp.M111.008094
Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
Science Translational Medicine
·
26 Oct 2011
·
doi:10.1126/scitranslmed.3002847
Lamins, guardians of the soma and the genome
Cell Cycle
·
01 Oct 2011
·
doi:10.4161/cc.10.19.17129
Deubiquitinases in cancer: new functions and therapeutic options
Oncogene
·
26 Sep 2011
·
doi:10.1038/onc.2011.443
Néstor–Guillermo progeria syndrome: A novel premature aging condition with early onset and chronic development caused by BANF1 mutations
American Journal of Medical Genetics Part A
·
19 Sep 2011
·
doi:10.1002/ajmg.a.34249
A conserved splicing mechanism of the LMNA gene controls premature aging
Human Molecular Genetics
·
29 Aug 2011
·
doi:10.1093/hmg/ddr385
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice
Blood
·
21 Jul 2011
·
doi:10.1182/blood-2011-04-348698
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Nature
·
05 Jun 2011
·
doi:10.1038/nature10113
Longevity-relevant regulation of autophagy at the level of the acetylproteome
Autophagy
·
01 Jun 2011
·
doi:10.4161/auto.7.6.15191
Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma
BMC Cancer
·
16 May 2011
·
doi:10.1186/1471-2407-11-172
Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome
The American Journal of Human Genetics
·
01 May 2011
·
doi:10.1016/j.ajhg.2011.04.010
Aging and chronic DNA damage response activate a regulatory pathway involving miR‐29 and p53
The EMBO Journal
·
26 Apr 2011
·
doi:10.1038/emboj.2011.124
Abstract 4970: Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma
Cancer Research
·
01 Apr 2011
·
doi:10.1158/1538-7445.AM2011-4970
The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities
Journal of Molecular Medicine
·
02 Mar 2011
·
doi:10.1007/s00109-011-0741-7
Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma
Human Mutation
·
24 Feb 2011
·
doi:10.1002/humu.21477
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
Journal of Cell Biology
·
21 Feb 2011
·
doi:10.1083/jcb.201008167
Comparative and demographic analysis of orang-utan genomes
Nature
·
26 Jan 2011
·
doi:10.1038/nature09687
Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6
Blood
·
13 Jan 2011
·
doi:10.1182/blood-2010-07-295147
Protease addiction and synthetic lethality in cancer
Frontiers in Oncology
·
01 Jan 2011
·
doi:10.3389/fonc.2011.00025
2010
Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model
Arthritis Research & Therapy
·
29 Dec 2010
·
doi:10.1186/ar3211
Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?
Aging
·
26 Dec 2010
·
doi:10.18632/aging.100262
Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells
PLoS ONE
·
11 Nov 2010
·
doi:10.1371/journal.pone.0015540
Mutational and Functional Analysis Reveals
ADAMTS18
Metalloproteinase as a Novel Driver in Melanoma
Molecular Cancer Research
·
01 Nov 2010
·
doi:10.1158/1541-7786.MCR-10-0262
Cancer Genomes
Clinical Chemistry
·
01 Nov 2010
·
doi:10.1373/clinchem.2010.152140
Absence or Inhibition of Matrix Metalloproteinase–8 Decreases Ventilator-Induced Lung Injury
American Journal of Respiratory Cell and Molecular Biology
·
01 Nov 2010
·
doi:10.1165/rcmb.2009-0034OC
Nuclear envelope alterations generate an aging‐like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
Aging Cell
·
21 Oct 2010
·
doi:10.1111/j.1474-9726.2010.00621.x
Resistance to Bleomycin-Induced Lung Fibrosis in MMP-8 Deficient Mice Is Mediated by Interleukin-10
PLoS ONE
·
07 Oct 2010
·
doi:10.1371/journal.pone.0013242
Autophagy, proteases and the sense of balance
Autophagy
·
01 Oct 2010
·
doi:10.4161/AUTO.6.7.13065
Autophagy, proteases and the sense of balance
Autophagy
·
01 Oct 2010
·
doi:10.4161/auto.6.7.13065
Matrix Metalloproteinase-19 Deficiency Promotes Tenascin-C Accumulation and Allergen-Induced Airway Inflammation
American Journal of Respiratory Cell and Molecular Biology
·
01 Sep 2010
·
doi:10.1165/rcmb.2008-0426OC
Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
Proceedings of the National Academy of Sciences
·
30 Aug 2010
·
doi:10.1073/PNAS.1002696107
Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
Proceedings of the National Academy of Sciences
·
30 Aug 2010
·
doi:10.1073/pnas.1002696107
Autophagy is essential for mouse sense of balance
Journal of Clinical Investigation
·
01 Jul 2010
·
doi:10.1172/JCI42601
Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer
Molecular Cancer
·
30 Jun 2010
·
doi:10.1186/1476-4598-9-170
672 Dissecting the protective role of vitamin D3 on colon cancer: new targets from the protein degradation machinery
European Journal of Cancer Supplements
·
01 Jun 2010
·
doi:10.1016/S1359-6349(10)71470-1
International network of cancer genome projects
Nature
·
15 Apr 2010
·
doi:10.1038/nature08987
The genome of a songbird
Nature
·
01 Apr 2010
·
doi:10.1038/nature08819
Comparative genomic analysis of the zebra finch degradome provides new insights into evolution of proteases in birds and mammals
BMC Genomics
·
01 Apr 2010
·
doi:10.1186/1471-2164-11-220
The regulatory crosstalk between kinases and proteases in cancer
Nature Reviews Cancer
·
19 Mar 2010
·
doi:10.1038/nrc2823
Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis
Oncogene
·
08 Mar 2010
·
doi:10.1038/onc.2010.49
Metalloproteases and the Degradome
Methods in Molecular Biology
·
01 Jan 2010
·
doi:10.1007/978-1-60327-299-5_1
Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
·
01 Jan 2010
·
doi:10.1016/j.bbamcr.2009.07.004
Autophagy and Aging: Lessons from Progeria Models
Advances in Experimental Medicine and Biology
·
01 Jan 2010
·
doi:10.1007/978-1-4419-7002-2_6
Vitamin D: Proteases, protease inhibitors and cancer
Cell Cycle
·
01 Jan 2010
·
doi:10.4161/cc.9.1.10266
2009
Protective roles of matrix metalloproteinases: From mouse models to human cancer
Cell Cycle
·
15 Nov 2009
·
doi:10.4161/cc.8.22.9956
A Role of Matrix Metalloproteinase-8 in Atherosclerosis
Circulation Research
·
23 Oct 2009
·
doi:10.1161/CIRCRESAHA.109.200279
Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation
Proceedings of the National Academy of Sciences
·
22 Sep 2009
·
doi:10.1073/pnas.0908507106
TheADAMTS12metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer
Journal of Cell Science
·
15 Aug 2009
·
doi:10.1242/jcs.050468
Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells
Journal of Clinical Investigation
·
03 Aug 2009
·
doi:10.1172/JCI37205
Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms
Human Molecular Genetics
·
10 Jul 2009
·
doi:10.1093/hmg/ddp315
Degradome expression profiling in human articular cartilage
Arthritis Research & Therapy
·
23 Jun 2009
·
doi:10.1186/ar2741
Genetic Inactivation of ADAMTS15 Metalloprotease in Human Colorectal Cancer
Cancer Research
·
01 Jun 2009
·
doi:10.1158/0008-5472.CAN-08-4155
Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis
Haematologica
·
18 Apr 2009
·
doi:10.3324/haematol.2008.001867
The Degradome database: mammalian proteases and diseases of proteolysis
Nucleic Acids Research
·
01 Jan 2009
·
doi:10.1093/nar/gkn570
Proteolytic Systems: Constructing Degradomes
Methods in Molecular Biology™
·
01 Jan 2009
·
doi:10.1007/978-1-60327-003-8_2
2008
Polymorphism +17 C/G in Matrix Metalloprotease MMP8 decreases lung cancer risk
BMC Cancer
·
01 Dec 2008
·
doi:10.1186/1471-2407-8-378
Accelerated ageing: from mechanism to therapy through animal models
Transgenic Research
·
18 Nov 2008
·
doi:10.1007/s11248-008-9226-z
Proteases: Multifunctional Enzymes in Life and Disease
Journal of Biological Chemistry
·
01 Nov 2008
·
doi:10.1074/jbc.R800035200
Microcephalia with mandibular and dental dysplasia in adult Zmpste24‐deficient mice
Journal of Anatomy
·
30 Oct 2008
·
doi:10.1111/j.1469-7580.2008.00970.x
Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
Blood
·
15 Sep 2008
·
doi:10.1182/blood-2008-04-149773
Erratum: Genome analysis of the platypus reveals unique signatures of evolution
Nature
·
01 Sep 2008
·
doi:10.1038/nature07253
Autophagy and aging: New lessons from progeroid mice
Autophagy
·
16 Aug 2008
·
doi:10.4161/auto.6478
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
Nature Medicine
·
29 Jun 2008
·
doi:10.1038/nm1786
Nitric oxide elicits functional MMP‐13 protein‐tyrosine nitration during wound repair
The FASEB Journal
·
21 May 2008
·
doi:10.1096/fj.07-103804
Loss of genes implicated in gastric function during platypus evolution
Genome Biology
·
15 May 2008
·
doi:10.1186/gb-2008-9-5-r81
Matrix metalloproteinase-8 is a regulator of the clinical aggressiveness of mammary tumours
Breast Cancer Research
·
01 May 2008
·
doi:10.1186/BCR1922
Genome analysis of the platypus reveals unique signatures of evolution
Nature
·
01 May 2008
·
doi:10.1038/nature06936
Matrix metalloproteinase-8 is a regulator of the clinical aggressiveness of mammary tumours
Breast Cancer Research
·
01 May 2008
·
doi:10.1186/bcr1922
Premature aging in mice activates a systemic metabolic response involving autophagy induction
Human Molecular Genetics
·
28 Apr 2008
·
doi:10.1093/hmg/ddn120
Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion
Cancer Research
·
15 Apr 2008
·
doi:10.1158/0008-5472.CAN-07-5154
Collagenase-2 Deficiency or Inhibition Impairs Experimental Autoimmune Encephalomyelitis in Mice
Journal of Biological Chemistry
·
01 Apr 2008
·
doi:10.1074/jbc.M709522200
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
The Journal of Cell Biology
·
31 Mar 2008
·
doi:10.1083/jcb.200801096
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy
·
16 Feb 2008
·
doi:10.4161/auto.5338
Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer
British Journal of Cancer
·
01 Feb 2008
·
doi:10.1038/sj.bjc.6604239
2007
The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway
Journal of Cell Science
·
15 Oct 2007
·
doi:10.1242/jcs.005751
Emerging roles of proteases in tumour suppression
Nature Reviews Cancer
·
01 Oct 2007
·
doi:10.1038/nrc2228
Involvement of specific matrix metalloproteinases during tumor necrosis factor/IFNγ–based cancer therapy in mice
Molecular Cancer Therapeutics
·
01 Sep 2007
·
doi:10.1158/1535-7163.MCT-07-0016
Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain
BMC Cancer
·
16 Aug 2007
·
doi:10.1186/1471-2407-7-162
Increased inflammation delays wound healing in mice deficient in collagenase‐2 (MMP‐8)
The FASEB Journal
·
28 Mar 2007
·
doi:10.1096/fj.06-7860com
LPS Responsiveness and Neutrophil Chemotaxis In Vivo Require PMN MMP-8 Activity
PLoS ONE
·
21 Mar 2007
·
doi:10.1371/journal.pone.0000312
Expanding the complexity of the human degradome: polyserases and their tandem serine protease domains
Frontiers in Bioscience
·
01 Jan 2007
·
doi:10.2741/2415
Collagenase‐2 (MMP‐8) and matrilysin‐2 (MMP‐26) expression in human wounds of different etiologies
Wound Repair and Regeneration
·
01 Jan 2007
·
doi:10.1111/j.1524-475X.2006.00184.x
2006
Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions
Cellular and Molecular Life Sciences
·
27 Nov 2006
·
doi:10.1007/s00018-006-6349-3
Matrix Metalloproteinase‐13 Is Highly Expressed in Destructive Periodontal Disease Activity
Journal of Periodontology
·
01 Nov 2006
·
doi:10.1902/jop.2006.050461
Membrane-Type 4 Matrix Metalloproteinase Promotes Breast Cancer Growth and Metastases
Cancer Research
·
15 May 2006
·
doi:10.1158/0008-5472.CAN-05-3012
Earlier Onset of Tumoral Angiogenesis in Matrix Metalloproteinase-19–Deficient Mice
Cancer Research
·
15 May 2006
·
doi:10.1158/0008-5472.CAN-05-4315
A functional link between the tumour suppressors ARF and p33ING1
Oncogene
·
10 Apr 2006
·
doi:10.1038/sj.onc.1209526
Comparative analysis of cancer genes in the human and chimpanzee genomes
BMC Genomics
·
26 Jan 2006
·
doi:10.1186/1471-2164-7-15
[no title info]
BMC Biochemistry
·
01 Jan 2006
·
doi:10.1186/1471-2091-7-9
2005
Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions
Blood
·
15 Dec 2005
·
doi:10.1182/blood-2005-05-2029
Comparative genomic analysis of human and chimpanzee proteases
Genomics
·
01 Dec 2005
·
doi:10.1016/j.ygeno.2005.07.009
Resistance of Collagenase-2 (Matrix Metalloproteinase-8)-Deficient Mice to TNF-Induced Lethal Hepatitis
The Journal of Immunology
·
01 Dec 2005
·
doi:10.4049/jimmunol.175.11.7642
Defective Prelamin A Processing Resulting From LMNA or ZMPSTE24 Mutations as the Cause of Restrictive Dermopathy
Archives of Dermatology
·
01 Nov 2005
·
doi:10.1001/archderm.141.11.1473-b
From Immature Lamin to Premature Aging: Molecular Pathways and Therapeutic Opportunities
Cell Cycle
·
20 Oct 2005
·
doi:10.4161/cc.4.12.2202
Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice
Proceedings of the National Academy of Sciences
·
18 Oct 2005
·
doi:10.1073/pnas.0507375102
MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMDMO)
Journal of Clinical Investigation
·
01 Oct 2005
·
doi:10.1172/JCI22900
Initial sequence of the chimpanzee genome and comparison with the human genome
Nature
·
01 Sep 2005
·
doi:10.1038/nature04072
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
Nature
·
03 Aug 2005
·
doi:10.1038/nature04019
Matrix Metalloproteinase-8 Deficiency Promotes Granulocytic Allergen-Induced Airway Inflammation
The Journal of Immunology
·
01 Aug 2005
·
doi:10.4049/jimmunol.175.4.2589
Genomic instability in laminopathy-based premature aging
Nature Medicine
·
26 Jun 2005
·
doi:10.1038/nm1266
Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors
Human Molecular Genetics
·
20 Apr 2005
·
doi:10.1093/hmg/ddi159
A genomic view of the complexity of mammalian proteolytic systems
Biochemical Society Transactions
·
01 Apr 2005
·
doi:10.1042/BST0330331
Carbohydrate- and Conformation-dependent Cargo Capture for ER-Exit
Molecular Biology of the Cell
·
01 Mar 2005
·
doi:10.1091/mbc.E04-08-0708
Human Polyserase-2, a Novel Enzyme with Three Tandem Serine Protease Domains in a Single Polypeptide Chain
Journal of Biological Chemistry
·
01 Jan 2005
·
doi:10.1074/jbc.M409139200
2004
Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification
Proceedings of the National Academy of Sciences
·
24 Nov 2004
·
doi:10.1073/pnas.0407788101
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP
The Journal of Cell Biology
·
22 Nov 2004
·
doi:10.1083/jcb.200408028
Protein Kinase C θ Is Highly Expressed in Gastrointestinal Stromal Tumors But Not in Other Mesenchymal Neoplasias
Clinical Cancer Research
·
15 Jun 2004
·
doi:10.1158/1078-0432.CCR-04-0630
Diet-Induced Obesity and Reduced Skin Cancer Susceptibility in Matrix Metalloproteinase 19-Deficient Mice
Molecular and Cellular Biology
·
01 Jun 2004
·
doi:10.1128/MCB.24.12.5304-5313.2004
Membrane-Bound Matrix Metalloproteinase-8 on Activated Polymorphonuclear Cells Is a Potent, Tissue Inhibitor of Metalloproteinase-Resistant Collagenase and Serpinase
The Journal of Immunology
·
01 Jun 2004
·
doi:10.4049/jimmunol.172.12.7791
Autophagy: molecular mechanisms, physiological functions and relevance in human pathology
Cellular and Molecular Life Sciences CMLS
·
01 Jun 2004
·
doi:10.1007/s00018-004-4012-4
Genome sequence of the Brown Norway rat yields insights into mammalian evolution
Nature
·
01 Apr 2004
·
doi:10.1038/nature02426
Differential Expression of Three Matrix Metalloproteinases, MMP-19, MMP-26, and MMP-28, in Normal and Inflamed Intestine and Colon Cancer
Digestive Diseases and Sciences
·
01 Apr 2004
·
doi:10.1023/B:DDAS.0000026314.12474.17
A Genomic Analysis of Rat Proteases and Protease Inhibitors
Genome Research
·
01 Apr 2004
·
doi:10.1101/gr.1946304
Use of a Multiple-Enzyme/Multiple-Reagent Assay System To Quantify Activity Levels in Samples Containing Mixtures of Matrix Metalloproteinases
Biochemistry
·
24 Feb 2004
·
doi:10.1021/bi036063m
Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors
Biological Chemistry
·
07 Jan 2004
·
doi:10.1515/BC.2004.058
Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies
The International Journal of Developmental Biology
·
01 Jan 2004
·
doi:10.1387/ijdb.041811af
Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
Biochemical and Biophysical Research Communications
·
01 Jan 2004
·
doi:10.1016/j.bbrc.2003.12.050
2003
Matrix Metalloproteinase-19 Expression in Dermal Wounds and by Fibroblasts in Culture
Journal of Investigative Dermatology
·
01 Nov 2003
·
doi:10.1046/j.1523-1747.2003.12533.x
AtFACE-2, a functional Prenylated Protein Protease from Arabidopsis thaliana Related to Mammalian Ras-converting Enzymes
Journal of Biological Chemistry
·
01 Oct 2003
·
doi:10.1074/jbc.M306700200
Loss of collagenase-2 confers increased skin tumor susceptibility to male mice
Nature Genetics
·
28 Sep 2003
·
doi:10.1038/ng1249
Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product
Proceedings of the National Academy of Sciences
·
28 Jul 2003
·
doi:10.1073/pnas.1633392100
Human and mouse proteases: a comparative genomic approach
Nature Reviews Genetics
·
01 Jul 2003
·
doi:10.1038/nrg1111
Identification and Characterization of ADAMTS-20 Defines a Novel Subfamily of Metalloproteinases-Disintegrins with Multiple Thrombospondin-1 Repeats and a Unique GON Domain
Journal of Biological Chemistry
·
01 Apr 2003
·
doi:10.1074/jbc.M211900200
Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans
Biochemical Journal
·
15 Mar 2003
·
doi:10.1042/BJ20021514
Human Autophagins, a Family of Cysteine Proteinases Potentially Implicated in Cell Degradation by Autophagy
Journal of Biological Chemistry
·
01 Feb 2003
·
doi:10.1074/jbc.M208247200
Membrane type-matrix metalloproteinases (MT-MMP)
Current Topics in Developmental Biology
·
01 Jan 2003
·
doi:10.1016/s0070-2153(03)54004-2
Matrix Metalloproteinases and Tumor Progression
Advances in Experimental Medicine and Biology
·
01 Jan 2003
·
doi:10.1007/978-1-4615-0081-0_9
2002
FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
The EMBO Journal
·
01 Dec 2002
·
doi:10.1093/emboj/cdf631
Activation of the Mitogen Activated Protein Kinase Extracellular Signal-Regulated Kinase 1 and 2 by the Nitric Oxide–cGMP–cGMP-Dependent Protein Kinase Axis Regulates the Expression of Matrix Metalloproteinase 13 in Vascular Endothelial Cells
Molecular Pharmacology
·
01 Oct 2002
·
doi:10.1124/mol.62.4.927
Strategies for MMP inhibition in cancer: innovations for the post-trial era
Nature Reviews Cancer
·
01 Sep 2002
·
doi:10.1038/nrc884
Protease degradomics: A new challenge for proteomics
Nature Reviews Molecular Cell Biology
·
01 Jul 2002
·
doi:10.1038/nrm858
Structural and Enzymatic Characterization of Drosophila Dm2-MMP, a Membrane-bound Matrix Metalloproteinase with Tissue-specific Expression
Journal of Biological Chemistry
·
01 Jun 2002
·
doi:10.1074/jbc.M200121200
Src-mediated coupling of focal adhesion kinase to integrin αvβ5 in vascular endothelial growth factor signaling
The Journal of Cell Biology
·
01 Apr 2002
·
doi:10.1083/jcb.200109079
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase–deficient mice
Nature Genetics
·
01 Apr 2002
·
doi:10.1038/ng871
Nitric oxide regulates matrix metalloprotease-13 expression and activity in endothelium
Kidney International
·
01 Mar 2002
·
doi:10.1046/j.1523-1755.2002.00224.x
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains
Gene
·
01 Jan 2002
·
doi:10.1016/S0378-1119(01)00861-7
2001
A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation
The Journal of Cell Biology
·
17 Dec 2001
·
doi:10.1083/jcb.200106147
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins
The Journal of Cell Biology
·
29 Oct 2001
·
doi:10.1083/jcb.200106070
The Urokinase Plasminogen Activator Receptor–Associated Protein/Endo180 Is Coexpressed with Its Interaction Partners Urokinase Plasminogen Activator Receptor and Matrix Metalloprotease-13 during Osteogenesis
Laboratory Investigation
·
01 Oct 2001
·
doi:10.1038/labinvest.3780354
Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas.
Cancer research
·
01 Oct 2001
·
pmid:11585740
Integrin αvβ1 Is an Adenovirus Coreceptor
Journal of Virology
·
01 Jun 2001
·
doi:10.1128/JVI.75.11.5405-5409.2001
Identification and Enzymatic Characterization of Two Diverging Murine Counterparts of Human Interstitial Collagenase (MMP-1) Expressed at Sites of Embryo Implantation
Journal of Biological Chemistry
·
01 Mar 2001
·
doi:10.1074/jbc.m007674200
La investigación oncológica en España
Arbor
·
28 Feb 2001
·
doi:10.3989/arbor.2001.i662.834
2000
Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity.
Cancer research
·
01 Sep 2000
·
pmid:10987280
Biochemical Characterization of the Catalytic Domain of Human Matrix Metalloproteinase 19
Journal of Biological Chemistry
·
01 May 2000
·
doi:10.1074/jbc.275.20.14809
Membrane Type 4 Matrix Metalloproteinase (MMP17) Has Tumor Necrosis Factor-α Convertase Activity but Does Not Activate Pro-MMP2
Journal of Biological Chemistry
·
01 May 2000
·
doi:10.1074/jbc.275.19.14046
ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism
Molecular Biology of the Cell
·
01 Apr 2000
·
doi:10.1091/mbc.11.4.1457
ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism
Molecular Biology of the Cell
·
01 Apr 2000
·
doi:10.1091/MBC.11.4.1457
Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.
Cancer research
·
15 Feb 2000
·
pmid:10706098
An overview of collagenase-3 expression in malignant tumors and analysis of its potential value as a target in antitumor therapies
Clinica Chimica Acta
·
01 Feb 2000
·
doi:10.1016/S0009-8981(99)00225-9
Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-γ is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1
Oncogene
·
13 Jan 2000
·
doi:10.1038/sj.onc.1203306
Assignment of the disulfide bonds of Ole e 1, a major allergen of olive tree pollen involved in fertilization
The Journal of Peptide Research
·
01 Jan 2000
·
doi:10.1034/j.1399-3011.2000.00138.x
Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase.
Journal of cell science
·
01 Jan 2000
·
pmid:10633074
1999
Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis
Annals of the Rheumatic Diseases
·
01 Nov 1999
·
doi:10.1136/ard.58.11.691
Human glandular kallikrein in breast milk, amniotic fluid, and breast cyst fluid.
Clinical chemistry
·
01 Oct 1999
·
pmid:10508124
Collagenase-3 Binds to a Specific Receptor and Requires the Low Density Lipoprotein Receptor-related Protein for Internalization
Journal of Biological Chemistry
·
01 Oct 1999
·
doi:10.1074/jbc.274.42.30087
Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate
Matrix Biology
·
01 Aug 1999
·
doi:10.1016/S0945-053X(99)00030-X
Immunoenzymatically determined pepsinogen C concentration in breast tumor cytosols: an independent favorable prognostic factor in node-positive patients.
Clinical cancer research : an official journal of the American Association for Cancer Research
·
01 Jul 1999
·
pmid:10430082
Collagenase‐2 and ‐3 Are Inhibited by Doxycycline in the Chronically Inflamed Lung in Bronchiectasis
Annals of the New York Academy of Sciences
·
01 Jun 1999
·
doi:10.1111/J.1749-6632.1999.TB07761.X
Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors.
Cancer research
·
01 Jun 1999
·
pmid:10363975
Collagenase 3 Is a Target of Cbfa1, a Transcription Factor of the runt Gene Family Involved in Bone Formation
Molecular and Cellular Biology
·
01 Jun 1999
·
doi:10.1128/mcb.19.6.4431
Identification and Chromosomal Location of Two Human Genes Encoding Enzymes Potentially Involved in Proteolytic Maturation of Farnesylated Proteins
Genomics
·
01 Jun 1999
·
doi:10.1006/geno.1999.5834
Evaluation of Some Newer Matrix Metalloproteinases
Annals of the New York Academy of Sciences
·
01 Jun 1999
·
doi:10.1111/j.1749-6632.1999.tb07672.x
Molecular Cloning and Structural and Functional Characterization of Human Cathepsin F, a New Cysteine Proteinase of the Papain Family with a Long Propeptide Domain
Journal of Biological Chemistry
·
01 May 1999
·
doi:10.1074/jbc.274.20.13800
Expression and regulation of collagenase‐3 (MMP‐13) in human malignant tumors
APMIS
·
01 Mar 1999
·
doi:10.1111/j.1699-0463.1999.tb01525.x
Cloning and Characterization of Human MMP-23, a New Matrix Metalloproteinase Predominantly Expressed in Reproductive Tissues and Lacking Conserved Domains in Other Family Members
Journal of Biological Chemistry
·
01 Feb 1999
·
doi:10.1074/jbc.274.8.4570
Induction of Collagenase-3 (MMP-13) Expression in Human Skin Fibroblasts by Three-dimensional Collagen Is Mediated by p38 Mitogen-activated Protein Kinase
Journal of Biological Chemistry
·
01 Jan 1999
·
doi:10.1074/jbc.274.4.2446
1998
Localization of the Human Membrane Type 4-Matrix Metalloproteinase Gene (MMP17) to Chromosome 12q24
Genomics
·
01 Dec 1998
·
doi:10.1006/geno.1998.5564
Genomic Structure and Chromosomal Localization of the Human Cathepsin O Gene (CTSO)
Genomics
·
01 Oct 1998
·
doi:10.1006/geno.1997.5180
Collagenase‐3 expression is associated with advanced local invasion in human squamous cell carcinomas of the larynx
The Journal of Pathology
·
01 Oct 1998
·
doi:10.1002/(SICI)1096-9896(1998100)186:2<144::AID-PATH147>3.0.CO;2-#
Collagenase 2 (MMP-8) Expression in Murine Tissue-remodeling Processes
Journal of Biological Chemistry
·
01 Sep 1998
·
doi:10.1074/jbc.273.37.23959
Structural Characterization and Chromosomal Localization of the Gene Encoding Human Biphenyl Hydrolase-Related Protein (BPHL)
Genomics
·
01 Aug 1998
·
doi:10.1006/geno.1998.5351
Breast and Prostate Cancer: An Analysis of Common Epidemiological, Genetic, and Biochemical Features*
Endocrine Reviews
·
01 Aug 1998
·
doi:10.1210/edrv.19.4.0337
High levels of expression of collagenase-3 (MMP-13) in pathological conditions associated with a foreign-body reaction
The Journal of Bone and Joint Surgery. British volume
·
01 Jul 1998
·
doi:10.1302/0301-620X.80B4.7952
Cathepsin Z, a Novel Human Cysteine Proteinase with a Short Propeptide Domain and a Unique Chromosomal Location
Journal of Biological Chemistry
·
01 Jul 1998
·
doi:10.1074/jbc.273.27.16816
Collagenase-3 (MMP-13) Expression in Chondrosarcoma Cells and Its Regulation by Basic Fibroblast Growth Factor
The American Journal of Pathology
·
01 Jul 1998
·
doi:10.1016/s0002-9440(10)65549-6
Collagenase-3 (matrix metalloproteinase-13) expression is induced in oral mucosal epithelium during chronic inflammation.
The American journal of pathology
·
01 Jun 1998
·
pmid:9626053
Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3
Biochemical Journal
·
15 Apr 1998
·
doi:10.1042/bj3310453
Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas.
Cancer research
·
15 Apr 1998
·
pmid:9563472
Secretion of Recombinant Pro- and Mature Fungal α-Sarcin Ribotoxin by the Methylotrophic YeastPichia pastoris:The Lys–Arg Motif Is Required for Maturation
Protein Expression and Purification
·
01 Apr 1998
·
doi:10.1006/prep.1997.0846
Differential Effects of Transforming Growth Factor-β on the Expression of Collagenase-1 and Collagenase-3 in Human Fibroblasts
Journal of Biological Chemistry
·
01 Apr 1998
·
doi:10.1074/jbc.273.16.9769
1997
Identification and Structural and Functional Characterization of Human Enamelysin (MMP-20),
Biochemistry
·
01 Dec 1997
·
doi:10.1021/bi972120y
Gene Characterization, Promoter Analysis, and Chromosomal Localization of Human Bleomycin Hydrolase
Journal of Biological Chemistry
·
01 Dec 1997
·
doi:10.1074/jbc.272.52.33298
Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions.
Cancer research
·
01 Nov 1997
·
pmid:9354453
Wheat flour peroxidase is a prominent allergen associated with baker's asthma
Clinical & Experimental Allergy
·
01 Oct 1997
·
doi:10.1111/j.1365-2222.1997.tb01149.x
Growth inhibition of human breast cancer cells by 1,25-dihydroxyvitamin D3 is accompanied by induction of apolipoprotein D expression.
Cancer research
·
15 Sep 1997
·
pmid:9307298
Activation of Progelatinase B (proMMP‐9) by Active Collagenase‐3 (MMP‐13)
European Journal of Biochemistry
·
01 Sep 1997
·
doi:10.1111/j.1432-1033.1997.00369.x
Nm23/PuF Does Not Directly Stimulate Transcription through the CT Element in Vivo
Journal of Biological Chemistry
·
01 Sep 1997
·
doi:10.1074/jbc.272.36.22526
Immunofluorometric assay of pepsinogen C and preliminary clinical applications.
Clinical chemistry
·
01 Aug 1997
·
pmid:9267315
Detection, isolation and complete amino acid sequence of an aeroallergenic protein from rapeseed flour
Clinical & Experimental Allergy
·
01 Jul 1997
·
doi:10.1111/J.1365-2222.1997.TB01219.X
Detection, isolation and complete amino acid sequence of an aeroallergenic protein from rapeseed flour
Clinical & Experimental Allergy
·
01 Jul 1997
·
doi:10.1046/j.1365-2222.1997.660843.x
Prostate-specific membrane antigen in breast carcinoma
The Lancet
·
01 May 1997
·
doi:10.1016/S0140-6736(05)61629-7
Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis.
Laboratory investigation; a journal of technical methods and pathology
·
01 May 1997
·
pmid:9166290
Biochemical characterization and crystalization of human Zn-α
2
-glycoprotein, a soluble class I major histocompatibility complex homolog
Proceedings of the National Academy of Sciences
·
29 Apr 1997
·
doi:10.1073/pnas.94.9.4626
Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines
Nature Medicine
·
01 Apr 1997
·
doi:10.1038/nm0497-395
The PLEES proteins: a family of structurally related enzymes widely distributed from bacteria to humans
Biochemical Journal
·
15 Mar 1997
·
doi:10.1042/BJ3220947
The PLEES proteins: a family of structurally related enzymes widely distributed from bacteria to humans
Biochemical Journal
·
15 Mar 1997
·
doi:10.1042/bj3220947
The Role of the C-terminal Domain of Human Collagenase-3 (MMP-13) in the Activation of Procollagenase-3, Substrate Specificity, and Tissue Inhibitor of Metalloproteinase Interaction
Journal of Biological Chemistry
·
01 Mar 1997
·
doi:10.1074/jbc.272.12.7608
Structural Analysis and Promoter Characterization of the Human Collagenase-3 Gene (MMP13)
Genomics
·
01 Mar 1997
·
doi:10.1006/geno.1996.4554
Characterization of the African Swine Fever Virus Structural Protein p14.5: A DNA Binding Protein
Virology
·
01 Mar 1997
·
doi:10.1006/viro.1996.8434
Identification and Characterization of a Novel Human Matrix Metalloproteinase with Unique Structural Characteristics, Chromosomal Location, and Tissue Distribution
Journal of Biological Chemistry
·
01 Feb 1997
·
doi:10.1074/jbc.272.7.4281
Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor alpha and transforming growth factor beta.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
·
01 Feb 1997
·
pmid:9040946
Site-directed Mutation of Nm23-H1
Journal of Biological Chemistry
·
01 Feb 1997
·
doi:10.1074/JBC.272.9.5525
Deletions and loss of expression of p16INK4a and p21Waf1 genes are associated with aggressive variants of mantle cell lymphomas.
Blood
·
01 Jan 1997
·
pmid:8978301
1996
The Helping Hand of Collagenase-3 (MMP-13): 2.7 Å Crystal Structure of its C-terminal Haemopexin-like Domain
Journal of Molecular Biology
·
01 Dec 1996
·
doi:10.1006/jmbi.1996.0661
Retinoic Acid-induced Expression of Apolipoprotein D and Concomitant Growth Arrest in Human Breast Cancer Cells Are Mediated through a Retinoic Acid Receptor RARα-dependent Signaling Pathway
Journal of Biological Chemistry
·
01 Dec 1996
·
doi:10.1074/jbc.271.50.32105
Ole e 3, An Olive‐Tree Allergen, Belongs to a Widespread Family of Pollen Proteins
European Journal of Biochemistry
·
01 Nov 1996
·
doi:10.1111/j.1432-1033.1996.00772.x
Divergence in properties of two closely related α‐amylase inhibitors of barley
Physiologia Plantarum
·
01 Nov 1996
·
doi:10.1111/j.1399-3054.1996.tb05707.x
Prostate specific antigen — a new constituent of breast cyst fluid
Breast Cancer Research and Treatment
·
01 Oct 1996
·
doi:10.1007/BF01806144
Fine Physical Mapping of the Human Matrix Metalloproteinase Genes Clustered on Chromosome 11q22.3
Genomics
·
01 Oct 1996
·
doi:10.1006/geno.1996.0557
Site-directed Mutagenesis of nm23-H1
Journal of Biological Chemistry
·
01 Oct 1996
·
doi:10.1074/JBC.271.41.25107
Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation
Journal of Biological Chemistry
·
01 Jul 1996
·
doi:10.1074/jbc.271.29.17124
Hormonal Regulation of the Human Pepsinogen C Gene in Breast Cancer Cells
Journal of Biological Chemistry
·
01 Jun 1996
·
doi:10.1074/jbc.271.25.15175
Functional Analysis of a p21 Mutant (Arg94→ Trp) Identified in a Human Breast Carcinoma
Journal of Biological Chemistry
·
01 Jun 1996
·
doi:10.1074/jbc.271.26.15782
Expression of collagenase-3 in the rat ovary during the ovulatory process
Journal of Endocrinology
·
01 Jun 1996
·
doi:10.1677/joe.0.1490405
Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance.
Cancer research
·
15 Apr 1996
·
pmid:8620487
Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.
Cancer research
·
01 Mar 1996
·
pmid:8640782
Biochemical Characterization of Human Collagenase-3
Journal of Biological Chemistry
·
01 Jan 1996
·
doi:10.1074/jbc.271.3.1544
Alternative splicing gives rise to two novel long isoforms of Zn-α2-glycoprotein, a member of the immunoglobulin superfamily
Gene
·
01 Jan 1996
·
doi:10.1016/0378-1119(95)00727-X
Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas
Human Genetics
·
01 Jan 1996
·
doi:10.1007/bf00218840
Differential Gene Expression in Tumor Metastasis: Nm23
Current Topics in Microbiology and Immunology
·
01 Jan 1996
·
doi:10.1007/978-3-642-61109-4_10
1995
Thiol-Disulfide Exchange of Ribonuclease Inhibitor Bound to Ribonuclease A EVIDENCE OF ACTIVE INHIBITOR-BOUND RIBONUCLEASE
Journal of Biological Chemistry
·
01 Dec 1995
·
doi:10.1074/jbc.270.48.28570
Arachidonic acid binds to apolipoprotein D: implications for the protein's function
FEBS Letters
·
05 Jun 1995
·
doi:10.1016/0014-5793(95)00484-Q
Cloning and Expression Analysis of a Novel Human Serine Hydrolase with Sequence Similarity to Prokaryotic Enzymes Involved in the Degradation of Aromatic Compounds
Journal of Biological Chemistry
·
01 May 1995
·
doi:10.1074/jbc.270.21.12926
A major baker's asthma allergen from rye flour is considerably more active than its barley counterpart
FEBS Letters
·
01 May 1995
·
doi:10.1016/0014-5793(95)00355-D
The human collagenase-3 (CLG3) gene is located on chromosome 11q22.3 clustered to other members of the matrix metalloproteinase gene family
Genomics
·
01 Apr 1995
·
doi:10.1016/0888-7543(95)80186-P
Mapping and Sequence of the Gene Encoding Protein pl7, a Major African Swine Fever Virus Structural Protein
Virology
·
01 Feb 1995
·
doi:10.1006/viro.1995.1039
Pepsinogen C is a new prognostic marker in primary breast cancer.
Journal of Clinical Oncology
·
01 Jan 1995
·
doi:10.1200/jco.1995.13.1.54
1994
Human cathepsin O. Molecular cloning from a breast carcinoma, production of the active enzyme in Escherichia coli, and expression analysis in human tissues.
The Journal of biological chemistry
·
28 Oct 1994
·
pmid:7929457
Apolipoprotein D gene induction by retinoic acid is concomitant with growth arrest and cell differentiation in human breast cancer cells.
The Journal of biological chemistry
·
28 Oct 1994
·
pmid:7929425
Structural and functional characterization of two allelic variants of human cystatin D sharing a characteristic inhibition spectrum against mammalian cysteine proteinases.
The Journal of biological chemistry
·
16 Sep 1994
·
pmid:8083219
Rye chromosome arm 3RS encodes a homodimeric inhibitor of insect α-amylase
Theoretical and Applied Genetics
·
01 Sep 1994
·
doi:10.1007/BF00226983
Rye Inhibitors of Animal α‐amylases Show Different Specifities, Aggregative Properties and IgE‐binding Capacities than Their Homologues from Wheat and Barley
European Journal of Biochemistry
·
01 Sep 1994
·
doi:10.1111/j.1432-1033.1994.00525.x
Relationship between serum prolactin levels and protein composition of breast secretions in nonlactating women.
The Journal of Clinical Endocrinology & Metabolism
·
01 Aug 1994
·
doi:10.1210/jcem.79.2.8045972
Cloning and expression analysis of the cDNA encoding rat Zn-α2-grycoprotein
Gene
·
01 Aug 1994
·
doi:10.1016/0378-1119(94)90014-0
Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.
The Journal of biological chemistry
·
17 Jun 1994
·
pmid:8207000
Overproduction and purification of biologically active native fungal α-sarcin in Escherichia coli
Gene
·
01 May 1994
·
doi:10.1016/0378-1119(94)90370-0
Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family.
Cancer research
·
15 Apr 1994
·
pmid:8174111
Isolation and characterization of an olive allergen‐like protein from lilac pollen
European Journal of Biochemistry
·
01 Apr 1994
·
doi:10.1111/j.1432-1033.1994.tb18728.x
Expression and prognostic significance of apolipoprotein D in breast cancer.
The American journal of pathology
·
01 Feb 1994
·
pmid:8311115
A protein related to brain microtubule-associated protein MAP1B is a component of the mammalian centrosome.
Journal of cell science
·
01 Feb 1994
·
pmid:8207082
Glucocorticoids and androgens up-regulate the Zn-?2-glycoprotein messenger RNA in human breast cancer cells
Breast Cancer Research and Treatment
·
01 Jan 1994
·
doi:10.1007/BF00666478
Mapping of the human Zn-α<sub>2</sub>-glycoprotein gene (AZGP1) to chromosome 7q22 by in situ hybridization
Cytogenetic and Genome Research
·
01 Jan 1994
·
doi:10.1159/000133708
Chromosomal mapping and nucleotide sequence of two tandem repeats of Atlantic salmon 5S rDNA
Cytogenetic and Genome Research
·
01 Jan 1994
·
doi:10.1159/000133792
1993
Human Zn- α 2 -glycoprotein: Complete genomic sequence, identification of a related pseudogene and relationship to class I major histocompatibility complex genes
Genomics
·
01 Dec 1993
·
doi:10.1016/S0888-7543(05)80359-3
Nucleotide sequence of a nucleoside triphosphate phosphohydrolase gene from African swine fever virus
Virus Research
·
01 Oct 1993
·
doi:10.1016/0168-1702(93)90016-G
The amino acid sequence of Ole e I, the major allergen from olive tree (Olea europaea) pollen
European Journal of Biochemistry
·
01 Sep 1993
·
doi:10.1111/j.1432-1033.1993.tb18208.x
Expression of pepsinogen C in human breast tumours and correlation with clinicopathologic parameters
British Journal of Cancer
·
01 Sep 1993
·
doi:10.1038/bjc.1993.399
Characterization of a new oriental-mustard (Brassica juncea) allergen, Bra
j IE: detection of an allergenic epitope
Biochemical Journal
·
01 Aug 1993
·
doi:10.1042/bj2930625
Human cystatin D. cDNA cloning, characterization of the Escherichia coli expressed inhibitor, and identification of the native protein in saliva.
The Journal of biological chemistry
·
25 Jul 1993
·
pmid:8340398
Role of the carboxy terminal region of β tubulin on microtubule dynamics through its interaction with the GTP phosphate binding region
FEBS Letters
·
05 Jul 1993
·
doi:10.1016/0014-5793(93)81067-A
Inhibitory effects of human cystatin C on plum pox potyvirus proteases
Plant Molecular Biology
·
01 Jul 1993
·
doi:10.1007/BF00047410
Cathepsin D in breast secretions from women with breast cancer
British Journal of Cancer
·
01 May 1993
·
doi:10.1038/bjc.1993.197
Barley Tetrameric Inhibitor of Insect α-amylases. Characterization of an Allelic Variant of the BTAI-CMb Subunit
Journal of Cereal Science
·
01 Mar 1993
·
doi:10.1006/jcrs.1993.1011
Structure and expression inE. coli of the gene coding for protein p10 of African swine fever virus
Archives of Virology
·
01 Mar 1993
·
doi:10.1007/BF01318999
A sequence variation in the human cystatin D gene resulting in an amino acid (Cys/Arg) polymorphism at the protein level
Human Genetics
·
01 Feb 1993
·
doi:10.1007/BF00202491
Zn-α2-glycoprotein levels in breast cancer cytosols and correlation with clinical, histological and biochemical parameters
European Journal of Cancer
·
01 Jan 1993
·
doi:10.1016/0959-8049(93)90068-Q
Genetic variants of the trypsin inhibitor from barley endosperm show different inhibitory activities
Plant Science
·
01 Jan 1993
·
doi:10.1016/0168-9452(93)90167-X
Localization of the human cystatin D gene (CST5) to chromosome 20p11.21 by in situ hybridization
Cytogenetic and Genome Research
·
01 Jan 1993
·
doi:10.1159/000133438
High-level expression in Escherichia coli of the gene coding for the major structural protein (p72) of African swine fever virus
Gene
·
01 Jan 1993
·
doi:10.1016/0378-1119(93)90134-O
1992
Isolation and characterization of a pepsin C zymogen produced by human breast tissues.
The Journal of biological chemistry
·
05 Dec 1992
·
pmid:1280267
Factors affecting protein composition of breast secretions from nonlactating women
Breast Cancer Research and Treatment
·
01 Oct 1992
·
doi:10.1007/BF01833522
Amino acid sequence and structural properties of protein p12, an African swine fever virus attachment protein.
Journal of virology
·
01 Jun 1992
·
pmid:1583732
Amino acid sequence and structural properties of protein p12, an African swine fever virus attachment protein
Journal of Virology
·
01 Jun 1992
·
doi:10.1128/jvi.66.6.3860-3868.1992
A gene homologous to topoisomerase II in African swine fever virus
Virology
·
01 Jun 1992
·
doi:10.1016/0042-6822(92)90558-7
Cholesterol and apolipoprotein D in gross cystic disease of the breast.
Clinical chemistry
·
01 May 1992
·
pmid:1582022
Quantification and molecular analysis of cathepsin D in breast cyst fluids
European Journal of Cancer
·
01 Apr 1992
·
doi:10.1016/0959-8049(92)90124-K
A Streptomyces glaucescens endodeoxyribonuclease which shows a strong preference for CC dinucleotide
European Journal of Biochemistry
·
01 Apr 1992
·
doi:10.1111/j.1432-1033.1992.tb16831.x
Wheat and barley allergens associated with baker's asthma. Glycosylated subunits of the α-amylase-inhibitor family have enhanced IgE-binding capacity
Biochemical Journal
·
15 Jan 1992
·
doi:10.1042/bj2810401
Identification of the major protein components in breast secretions from women with benign and malignant breast diseases.
Cancer research
·
01 Jan 1992
·
pmid:1727390
1991
A new distinct group of 2 S albumins from rapeseed
FEBS Letters
·
16 Dec 1991
·
doi:10.1016/0014-5793(91)81419-9
Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor.
The Journal of biological chemistry
·
25 Oct 1991
·
pmid:1939105
A general method to cleave a known DNA sequence at any site.
BioTechniques
·
01 Oct 1991
·
pmid:1665337
Human Zn‐α2‐glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues
FEBS Letters
·
23 Sep 1991
·
doi:10.1016/0014-5793(91)81271-9
Amino acid compositions and sequence analysis of the major low Mr globulins from Triticum monococcum L. endosperm
Journal of Cereal Science
·
01 Sep 1991
·
doi:10.1016/s0733-5210(09)80132-x
Wheat Inhibitors of Heterologous α-Amylases
Plant Physiology
·
01 Jul 1991
·
doi:10.1104/pp.96.3.768
Structural analysis of the small chain of the 2S albumin, napin nIII, from rapeseed. Chemical and spectroscopic evidence of an intramolecular bond formation
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
·
01 Jun 1991
·
doi:10.1016/0167-4838(91)90568-K
Location of phosphorylated residues in human respiratory syncytial virus phosphoprotein
Journal of General Virology
·
01 Jun 1991
·
doi:10.1099/0022-1317-72-6-1455
Tau-related protein present in paired helical filaments has a decreased tubulin binding capacity as compared with microtubule-associated protein tau
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
·
01 Apr 1991
·
doi:10.1016/0925-4439(91)90005-T
GCDFP-70 protein in cyst fluid identified as albumin and used to classify cysts in women with breast gross cystic disease.
Clinical chemistry
·
01 Apr 1991
·
pmid:2015669
Evidence of a Correlation between CA15.3 and Prolactin Serum Levels after TRH Administration in Women with Gross Cystic Breast Disease
The International Journal of Biological Markers
·
01 Jan 1991
·
doi:10.1177/172460089100600106
1990
Apolipoprotein D is the major protein component in cyst fluid from women with human breast gross cystic disease
Biochemical Journal
·
01 Nov 1990
·
doi:10.1042/bj2710803
Apolipoprotein D is the major protein component in cyst fluid from women with human breast gross cystic disease
Biochemical Journal
·
01 Nov 1990
·
doi:10.1042/BJ2710803
Isolation of three allergenic fractions of the major allergen from Olea europea pollen and N-terminal amino acid sequence
Biochemical and Biophysical Research Communications
·
01 Oct 1990
·
doi:10.1016/0006-291X(90)90704-Q
Sequence and evolutionary relationships of African swine fever virus thymidine kinase
Virology
·
01 Sep 1990
·
doi:10.1016/0042-6822(90)90409-K
Phosphorylation of a neuronal-specific beta-tubulin isotype.
The Journal of biological chemistry
·
15 Aug 1990
·
pmid:2199448
Location and characterization of the three carbohydrate prosthetic groups of human protein HC
FEBS Letters
·
18 Jun 1990
·
doi:10.1016/0014-5793(90)81531-R
SYNERGISTIC EFFECT IN THE EXTRACTION OP PHENOL FROM AQUEOUS SOLUTIONS WITH MIXTURES OF N-BUTYLACETATE AND ACETOPHENONE
Solvent Extraction and Ion Exchange
·
01 Jun 1990
·
doi:10.1080/07366299008918032
β‐Turns as structural motifs for the proteolytic processing of seed proteins
FEBS Letters
·
24 Apr 1990
·
doi:10.1016/0014-5793(90)81375-X
Mapping and sequence of the gene coding for protein p72, the major capsid protein of african swine fever virus
Virology
·
01 Apr 1990
·
doi:10.1016/0042-6822(90)90432-Q
Determination of polyprotein processing sites by amino terminal sequencing of nonstructural proteins encoded by plum pox potyvirus
Virus Research
·
01 Feb 1990
·
doi:10.1016/0168-1702(90)90001-R
Genomic Organisation of a Virulent Isolate of Porcine Transmissible Gastroenteritis Virus
Advances in Experimental Medicine and Biology
·
01 Jan 1990
·
doi:10.1007/978-1-4684-5823-7_48
1989
Sequence of the coding regions from the 3.0 kb and 3.9 kb mRNA
Archives of Virology
·
01 Sep 1989
·
doi:10.1007/BF01311354
IgA-CK-BB complex with CK-MB electrophoretic mobility can lead to erroneous diagnosis of acute myocardial infarction.
Clinical chemistry
·
01 Sep 1989
·
pmid:2776341
Gly-Gly-X, a novel consensus sequence for the proteolytic processing of viral and cellular proteins.
The Journal of biological chemistry
·
05 Jun 1989
·
pmid:2722819
A barley flour inhibitor of insect α‐amylase is a major allergen associated with baker's asthma disease
FEBS Letters
·
08 May 1989
·
doi:10.1016/0014-5793(89)80444-2
Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases.
The Journal of experimental medicine
·
01 May 1989
·
doi:10.1084/jem.169.5.1771
Predict7, a program for protein structure prediction
Biochemical and Biophysical Research Communications
·
01 Mar 1989
·
doi:10.1016/0006-291X(89)90049-1
1988
Mapping and sequence of the gene encoding protein p37, A major structural protein of African swine fever virus
Virus Genes
·
01 Jan 1988
·
doi:10.1007/BF00572708
1985
Complete amino acid sequence of the Aspergillus cytotoxin mitogillin
Biochemistry
·
01 Feb 1985
·
doi:10.1021/bi00325a008
1984
The primary structure of the cytotoxin restrictocin
European Journal of Biochemistry
·
01 Sep 1984
·
doi:10.1111/j.1432-1033.1984.tb08415.x
Conformational studies of the human complex-forming glycoprotein, heterogeneous in charge: protein HC
Biochemistry
·
13 Mar 1984
·
doi:10.1021/bi00301a033
The complete amino acid sequence of human complex-forming glycoprotein heterogeneous in charge (protein HC) from one individual
Archives of Biochemistry and Biophysics
·
01 Feb 1984
·
doi:10.1016/0003-9861(84)90021-3
1983
Neutral microprotein, a novel human plasma and urinary protein associated with a yellow-brown chromophore. Isolation from protein HC preparations and partial characterization
Biochemical and Biophysical Research Communications
·
01 Nov 1983
·
doi:10.1016/0006-291X(83)91561-9
1982
Amino acid sequence homologies in alfa-sarcin, restrictocin and mitogillin
Biochemical and Biophysical Research Communications
·
01 Sep 1982
·
doi:10.1016/0006-291X(82)91868-X
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:001463300600032
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000172121800801
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000172121800015
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000208733101843
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000335419603297
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000342830900129
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000432419700200
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000404127001018
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000404127001016
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000489313103213
Strategies for Cloning New MMPs and TIMPs
Matrix Metalloproteinase Protocols
·
[no date info]
·
doi:10.1385/1-59259-046-2:025
[no title info]
[no publisher info]
·
[no date info]
·
issn:0003987X 0003987X
Protease Genomics and the Cancer Degradome
The Cancer Degradome
·
[no date info]
·
doi:10.1007/978-0-387-69057-5_1
ISSN 0034-8635 - Revista de occidente
[no publisher info]
·
[no date info]
·
issn:00348635
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000440252400002
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000404127006336
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000668898600381
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1991GM03900099
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1991GJ84100002
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1992KA26300086
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1993KN46401191
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1993LN30500062
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1993MK10000074
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1994NE84900010
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:A1994NR29600041
ISSN 0067-8694 - Biochemical Society Symposia
[no publisher info]
·
[no date info]
·
issn:00678694
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000080612000135
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000080712700014
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000080612000047
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000083673501081
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000226117900514
Web of Science
[no publisher info]
·
[no date info]
·
wosuid:WOS:000310364400085